PROPARGYLAMINE
Synonym(s):2-Propynylamine;3-Amino-1-propyne
- CAS NO.:2450-71-7
- Empirical Formula: C3H5N
- Molecular Weight: 55.08
- MDL number: MFCD00008198
- EINECS: 219-513-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-21 22:41:43
What is PROPARGYLAMINE?
Chemical properties
clear colorless to yellow liquid
The Uses of PROPARGYLAMINE
Propargylamine is used in the synthesis of a chiral, a fluorescent macrocycle by 1,3-dipolar cycloaddition of propargyl amides of carbohydrate-linked amino acids and 9,10-bis(azidomethyl)anthracene. It acts as an intermediate in the production of drugs.
The Uses of PROPARGYLAMINE
A useful intermediates in the preparation of drugs or pesticides.
The Uses of PROPARGYLAMINE
Synthesis of a chiral, fluorescent macrocycle by 1,3-dipolar cycloaddition of propargyl amides of carbohydrate-linked amino acids and 9,10-bis(azidomethyl)anthracene.
What are the applications of Application
Propargylamine is a useful cycloaddition reagent
Enzyme inhibitor
This alkynyl amine HCCCH2–NH2 (FWfree-base = 55.08 g/mol), also known as propargylamine and 3-amino-1-propyne, is a toxic liquid that boils at 83°C. The water-soluble hydrochloride melts at 179-182°C. Target(s): aldehyde dehydrogenase; diamine oxidase, or amine oxidase [copper-containing]; glycine cleavage complex, or glycine synthase; and monoamine oxidase, or amine oxidase [flavin-containing].
Properties of PROPARGYLAMINE
Boiling point: | 84 °C |
Density | 0.86 |
refractive index | n |
Flash point: | 39 °F |
storage temp. | 2-8°C |
solubility | soluble in Chloroform, Ethyl Acetate |
form | Liquid |
pka | 7.89±0.29(Predicted) |
color | Clear colorless to yellow |
Water Solubility | miscible |
Sensitive | Air Sensitive |
BRN | 773681 |
Dielectric constant | 6.6500000000000004 |
CAS DataBase Reference | 2450-71-7(CAS DataBase Reference) |
NIST Chemistry Reference | Propargylamine(2450-71-7) |
EPA Substance Registry System | 2-Propyn-1-amine (2450-71-7) |
Safety information for PROPARGYLAMINE
Signal word | Danger |
Pictogram(s) |
Flame Flammables GHS02 Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H225:Flammable liquids H302:Acute toxicity,oral H310:Acute toxicity,dermal H314:Skin corrosion/irritation |
Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for PROPARGYLAMINE
Abamectin manufacturer
JSK Chemicals
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