Propamidine
- CAS NO.：104-32-5
- Empirical Formula: C17H20N4O2
- Molecular Weight: 312.37
- MDL number: MFCD00866601
- EINECS: 203-195-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is Propamidine?
The Uses of Propamidine
as isethionate.
Definition
ChEBI: A polyether that is the bis(4-guanidinophenyl) ether of propane-1,3-diol. Used (as its isethionate salt) for the treatment of minor eye or eyelid infections, such as conjunctivitis and blepharitis.
Pharmaceutical Applications
A synthetic diamidine formulated as the isethionate or as
dibromopropamidine isethionate for topical administration
to the eye. Resistant clinical isolates of Acanthamoeba
have been identified. It is available over the counter in eye
drops.
Its activity against bacterial pathogens is poor, but it exhibits
specific activity against Acanthamoeba spp. Reduction in
sensitivity of Acanthamoeba during encystation might reflect
changes in drug uptake. It is still recommended for aggressive
treatment of amebic keratitis (in combination with neomycin
or other agents), but is not well tolerated.
Properties of Propamidine
| Boiling point: | 497.3±55.0 °C(Predicted) |
| Density | 1.25±0.1 g/cm3(Predicted) |
| pka | 12.75±0.50(Predicted) |
Safety information for Propamidine
Computed Descriptors for Propamidine
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid DIETHYL AMINOMALONATE HYDROCHLORIDE 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
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