Poziotinib (HM781-36B)
- CAS NO.：1092364-38-9
- Empirical Formula: C23H21Cl2FN4O3
- Molecular Weight: 491.34
- MDL number: MFCD28044290
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is Poziotinib (HM781-36B)?
Description
Poziotinib is a TKI that covalently and irreversibly inhibits EGFR and HER2, and is unique because of its small terminal group and flexible quinazoline core. Its small size and flexibility allow it to evade the steric hindrance which affects other EGFR TKIs [138].
The Uses of Poziotinib (HM781-36B)
Poziotinib can be used to inhibit the growth of cancer cells.
Properties of Poziotinib (HM781-36B)
| Melting point: | 187 - 190° C |
| Boiling point: | 629.7±55.0 °C(Predicted) |
| Density | 1.409±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer, Under inert atmosphere |
| solubility | Chloroform (Slightly), DMSO (Slightly, Sonicated) |
| form | Solid |
| pka | 5.35±0.30(Predicted) |
| color | White to Pale Beige |
| CAS DataBase Reference | 1092364-38-9 |
Safety information for Poziotinib (HM781-36B)
Computed Descriptors for Poziotinib (HM781-36B)
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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