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HomeProduct name listPoziotinib (HM781-36B)

Poziotinib (HM781-36B)

Poziotinib (HM781-36B) Structural

What is Poziotinib (HM781-36B)?

Description

Poziotinib is a TKI that covalently and irreversibly inhibits EGFR and HER2, and is unique because of its small terminal group and flexible quinazoline core. Its small size and flexibility allow it to evade the steric hindrance which affects other EGFR TKIs [138].

The Uses of Poziotinib (HM781-36B)

Poziotinib can be used to inhibit the growth of cancer cells.

Properties of Poziotinib (HM781-36B)

Melting point: 187 - 190° C
Boiling point: 629.7±55.0 °C(Predicted)
Density  1.409±0.06 g/cm3(Predicted)
storage temp.  -20°C Freezer, Under inert atmosphere
solubility  Chloroform (Slightly), DMSO (Slightly, Sonicated)
form  Solid
pka 5.35±0.30(Predicted)
color  White to Pale Beige
CAS DataBase Reference 1092364-38-9

Safety information for Poziotinib (HM781-36B)

Computed Descriptors for Poziotinib (HM781-36B)

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