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HomeProduct name listPNU 37883 hydrochloride

PNU 37883 hydrochloride

PNU 37883 hydrochloride Structural

What is PNU 37883 hydrochloride?

What are the applications of Application

U-37883A is a potent inhibitor of vascular smooth muscle KIR6 channels

Biological Activity

Novel antagonist selective for the vascular form of K ATP channel; inhibits K ATP currents in isolated mesenteric artery smooth muscle cells (K d = 65 nM) but not in cardiac or skeletal myocytes. In vivo, inhibits blood vessel relaxation and hypotension induced by pinacidil. Displays weak diuretic effects.

storage

room temperature (desiccate)

Properties of PNU 37883 hydrochloride

RTECS  QD9865500
storage temp.  2-8°C
solubility  DMSO: ~23 mg/mL
form  powder
color  white

Safety information for PNU 37883 hydrochloride

Computed Descriptors for PNU 37883 hydrochloride

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