Pinostrobin
- CAS NO.:480-37-5
- Empirical Formula: C16H14O4
- Molecular Weight: 270.28
- MDL number: MFCD06858342
- EINECS: 207-548-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:16
![Pinostrobin Structural](https://img.chemicalbook.in/CAS/GIF/480-37-5.gif)
What is Pinostrobin?
Description
Pinostrobin is a flavonoid with diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It induces quinone reductase (QR) in murine hepatoma cells with a QR doubling concentration of 500 nM. Pinostrobin inhibits TNF-α and IL-1β production in RAW 264.7 macrophages (IC50s = 17.28 and 23.5 μM, respectively) and in LPS-stimulated rats (48.6 and 55% reduction, respectively). Pinostrobin also shows selective cytotoxicity for CCRF-CEM leukemia cells (IC50 = 10.2 μM) in a panel of eight cancer cell lines (IC50s = >30 μM).
The Uses of Pinostrobin
Pinostrombin is a useful research chemical that can be used for chemical fingerprinting, isolating, and characterizing of polyphenol compounds. It can also be used as a potential compound for TMPRSS2 inhibition for Covid-19 therapy.
definition
ChEBI: A monohydroxyflavanone that is (2S)-flavanone substituted by a hydroxy group at position 5 and a methoxy group at position 7 respectively.
Properties of Pinostrobin
Melting point: | 100°C |
Boiling point: | 494.9±45.0 °C(Predicted) |
Density | 1.284±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | DMF: 20 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 12 mg/ml |
form | A crystalline solid |
pka | 7.40±0.40(Predicted) |
color | White to yellow |
Safety information for Pinostrobin
Signal word | Warning |
Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Pinostrobin
Abamectin manufacturer
CHROMOSYNTH PVT LTD
New Products
3-Pyridineacrylic acid 3-Bromo-4-fluorophenol N-Boc-Ethylenediamine cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate 4-Aminotetrahydropyran hydrochloride 4,5-Dibromopyridazin-3-one N-Benzyl-3-hydroxypiperidine 2-Methyl-4-nitrobenzoic acid 2-(4-bromophenyl)-2-methylpropanoic acid 4-Acetyl-2-methylbenzoicacid Acetyl-meldrum's acid Ethyl-4-Pyrazole carboxylate 2,6-Pyridinedimethanol 5,7-Dichloro-3H-Imidazo[4,5-B]Pyridine 5-Bromo-2-Methoxy-4-Methyl-3-Nitropyridine 2-Fluoro-5-Iodopyridine 2-Fluoro-5-Methylpyridine 2-Chloro-3-Bromo-5-Amiopyridine METHYL-4-(BUTYRYLAMINO)3-METHYL-5-NITROBENZOATE TRANS-CYCLOBUTANE-1,2- DICARBOXYLIC ACID 5-Nitro indazole R-(-)-5-(2-AMINO-PROPYL)-2-METHOXY-BENZENESULFONAMIDE 1,3-cyclohexanedione 4-AminophenaethylalcholRelated products of tetrahydrofuran
![](https://img.chemicalbook.in/CAS/20180808/GIF/122-84-9.gif)
![](https://img.chemicalbook.in/StructureFile/ChemBookStructure22/GIF/CB41041264.gif)
![](https://img.chemicalbook.in/CAS/GIF/20115-23-5.gif)
![](https://img.chemicalbook.in/CAS/GIF/103-82-2.gif)
![](https://img.chemicalbook.in/CAS/GIF/88-12-0.gif)
![](https://img.chemicalbook.in/CAS/20181022/GIF/9003-39-8.gif)
![](https://img.chemicalbook.in/CAS/GIF/18479-58-8.gif)
![](https://img.chemicalbook.in/CAS/GIF/456-55-3.gif)
You may like
-
480-37-5 5-Hydroxy -7-methoxy Flavanone (or) Pinostrobin 98%View Details
480-37-5 -
23761-23-1 98+View Details
23761-23-1 -
2516-34-9 Cyclobutylamine 98+View Details
2516-34-9 -
Methyl syringate 98+View Details
884-35-5 -
23462-75-1 2H-PYRAN-3(4H)-ONE, DIHYDRO- 98+View Details
23462-75-1 -
136725-53-6 98+View Details
136725-53-6 -
500-22-1 3- Pyridinecarboxaldehdye 99%View Details
500-22-1 -
872-85-5 99%View Details
872-85-5