Phthalhydrazide
Synonym(s):2,3-Dihydro-1,4-phthalazinedione
- CAS NO.：1445-69-8
- Empirical Formula: C8H6N2O2
- Molecular Weight: 162.15
- MDL number: MFCD00006888
- EINECS: 215-893-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-21 22:41:43
What is Phthalhydrazide?
Chemical properties
WHITE POWDER AND CHUNKS
The Uses of Phthalhydrazide
Phthalhydrazide is a reagent used in the synthesis of various pyrazolophthalazine derivatives is and used in medicine double hydrazine phthalocyanine work intermediates.
The Uses of Phthalhydrazide
Phthalic Hydrazide is a reagent in the synthesis in various pyrazolophthalazine derivatives.
What are the applications of Application
Phthalhydrazide is a reagent used in the synthesis of various pyrazolophthalazine derivatives
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 5, p. 111, 1968 DOI: 10.1002/jhet.5570050120
Synthesis Reference(s)
Journal of the American Chemical Society, 84, p. 966, 1962 DOI: 10.1021/ja00865a018
Purification Methods
Recrystallise it twice from 0.1M KOH [Merenyi et al. J Am Chem Soc 108 7716 1986], EtOH or dimethylformamide and it sublimes >300o. [Beilstein 24 H 371, 24 II 194.]
Properties of Phthalhydrazide
| Melting point: | >300 °C (lit.) |
| Boiling point: | 288.82°C (rough estimate) |
| Density | 1.3264 (rough estimate) |
| refractive index | 1.5770 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Soluble in acetone and acetic acid. |
| pka | 10.70±0.20(Predicted) |
| form | Powder and Chunks |
| color | White |
| BRN | 135926 |
| CAS DataBase Reference | 1445-69-8(CAS DataBase Reference) |
Safety information for Phthalhydrazide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Phthalhydrazide
| InChIKey | KGLPWQKSKUVKMJ-UHFFFAOYSA-N |
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