Phenylarsine oxide

Synonym(s):Arzene;Oxophenylarsine;PAO;PAO, Oxophenylarsine, PTP Inhibitor IX, PDI Inhibitor II, Protein Disulfide Isomerase Inhibitor II;Phenylarsine Oxide - CAS 637-03-6 - Calbiochem

CAS NO.：637-03-6
Empirical Formula: C6H5AsO
Molecular Weight: 168.02
MDL number: MFCD00001990
EINECS: 211-275-3
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is Phenylarsine oxide?

Chemical properties

WHITE TO ALMOST WHITE CRYSTALS OR CRYST. POWDER

The Uses of Phenylarsine oxide

Phenylarsine oxide is used as a poultry coccidiostat in veterinary medicine. It is also used in a membrane-permeable protein tyrosine phosphatase inhibitor.

The Uses of Phenylarsine oxide

Pesticide.

What are the applications of Application

Phenylarsine oxide is a membrane-permeable PTPase inhibitor

Definition

ChEBI: An arsine oxide derived from phenylarsine.

General Description

Phenylarsine oxide (PhAsO⁴) is a bifunctional SH group chemical. It is hydrophobic in nature.

Biochem/physiol Actions

Phenylarsine oxide?(PAO) can reduce the motility and sustainability of Setaria cervi. It has the ability to stimulate cyclosporin A-sensitive transition in the presence of EGTA (ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid). It acts as a stimulator of mitochondrial ion fluxes.

Safety Profile

Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits toxic fumes of As. See also ARSENIC COMPOUNDS

Properties of Phenylarsine oxide

Melting point:	145-148 °C
storage temp.	Poison room
solubility	DMSO: 50 mg/mL
form	powder
color	white to yellow
Water Solubility	Soluble in dimethyl sulfoxide, chloroform, benzene, ether, ethanol, 50:50 dimethyl sulfoxide:1 M hydrochloric acid (3.0 mg/ml) and toluene. Insoluble in water.
Merck	14,6949
BRN	2935227
Stability:	Stable.
CAS DataBase Reference	637-03-6(CAS DataBase Reference)
EPA Substance Registry System	Oxophenylarsine (637-03-6)

Safety information for Phenylarsine oxide

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Environment GHS09
GHS Hazard Statements	H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.