OKADAIC ACID SODIUM SALT

Synonym(s):OA

CAS NO.：209266-80-8
Empirical Formula: C44H67NaO13
Molecular Weight: 826.98
MDL number: MFCD00210208
EINECS: 606-670-6
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-30 15:45:59

What is OKADAIC ACID SODIUM SALT?

Chemical properties

white to off-white solid

The Uses of OKADAIC ACID SODIUM SALT

Potent inhibitor of serine/threonine-specific protein phosphatases 1 and 2A (PP1 and PP2A). Does not inhibit tyrosine or alkaline phosphatases

What are the applications of Application

Okadaic acid sodium salt is a naturally occurring inhibitor of PP1A and PP2A/PP2B

Biochem/physiol Actions

Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.

storage

Store at -20°C (desiccate)

Properties of OKADAIC ACID SODIUM SALT

storage temp.	-20°C
solubility	Soluble in DMSO or ethanol
form	film
color	translucent

Safety information for OKADAIC ACID SODIUM SALT

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H315:Skin corrosion/irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.