OKADAIC ACID POTASSIUM SALT
Synonym(s):OA;Okadaic Acid, Potassium Salt - CAS 155751-72-7 - Calbiochem
- CAS NO.:155751-72-7
- Empirical Formula: C44H67KO13
- Molecular Weight: 843.09
- MDL number: MFCD00213389
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is OKADAIC ACID POTASSIUM SALT?
The Uses of OKADAIC ACID POTASSIUM SALT
Okadaic Acid, Potassium Salt has been used as a response modifier in the study of large granular lymphocyte and T-cell biochemistry. In addition to inhibitive activities it is a tumor promoter and has been used to study nitric oxide metabolism, apoptosis, cell cycle and calcium signaling. It is also used as a PP1/PP2A/PP2B/PP2C inhibitor, used to study tumor promotion/NO metabolism/apoptosis
What are the applications of Application
Okadaic Acid, Potassium Salt is a PP1/PP2A/PP2B/PP2C inhibitor, used to study tumor promotion/NO metabolism/apoptosis
Biochem/physiol Actions
Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.
Properties of OKADAIC ACID POTASSIUM SALT
storage temp. | -20°C |
solubility | H2O: 0.1 mg/mL |
form | powder |
color | white |
Water Solubility | Soluble in DMSO or ethanol. Soluble in water at 0.1mg/ml. Also soluble in methanol |
Safety information for OKADAIC ACID POTASSIUM SALT
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H315:Skin corrosion/irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for OKADAIC ACID POTASSIUM SALT
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