OKADAIC ACID POTASSIUM SALT

Synonym(s):OA;Okadaic Acid, Potassium Salt - CAS 155751-72-7 - Calbiochem

CAS NO.：155751-72-7
Empirical Formula: C44H67KO13
Molecular Weight: 843.09
MDL number: MFCD00213389
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is OKADAIC ACID POTASSIUM SALT?

The Uses of OKADAIC ACID POTASSIUM SALT

Okadaic Acid, Potassium Salt has been used as a response modifier in the study of large granular lymphocyte and T-cell biochemistry. In addition to inhibitive activities it is a tumor promoter and has been used to study nitric oxide metabolism, apoptosis, cell cycle and calcium signaling. It is also used as a PP1/PP2A/PP2B/PP2C inhibitor, used to study tumor promotion/NO metabolism/apoptosis

What are the applications of Application

Okadaic Acid, Potassium Salt is a PP1/PP2A/PP2B/PP2C inhibitor, used to study tumor promotion/NO metabolism/apoptosis

Biochem/physiol Actions

Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.

Properties of OKADAIC ACID POTASSIUM SALT

storage temp.	-20°C
solubility	H₂O: 0.1 mg/mL
form	powder
color	white
Water Solubility	Soluble in DMSO or ethanol. Soluble in water at 0.1mg/ml. Also soluble in methanol

Safety information for OKADAIC ACID POTASSIUM SALT

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H315:Skin corrosion/irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.