Norgestrel
Synonym(s):Levonorgestrel;(±)-Norgestrel;(17α)-(±)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one;13β-Ethyl-17α-ethynyl-17β-hydroxygon-4-en-3-one;17α-Ethynyl-18-homo-19-nor-testosterone
- CAS NO.：6533-00-2
- Empirical Formula: C21H28O2
- Molecular Weight: 312.45
- MDL number: MFCD01546387
- EINECS: 229-433-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-11-07 17:33:14
What is Norgestrel?
Description
Norgestrel is a synthetic progestin and a racemic mixture of dextronorgestrel and levonorgestrel , of which levonorgestrel is the biologically active component. In vivo, norgestrel administered via intrauterine device (IUD) prevents pregnancy in rats. Formulations containing nogestrel have been used as contraceptives.
The Uses of Norgestrel
A metabolite of Norgestrel.
What are the applications of Application
Norgestrel is a synthetic progesterone analog
Indications
Norgestrel in combination with ethinyl estradiol is indicated for the prevention of pregnancy in women who elect to use this product as a method of contraception.
Background
Norgestrel is synthetic steroidal progestin that is used in combination with ethinyl estradiol for oral contraception. Norgestrel is composed of a racemic mixture of two stereoisomers, dextronorgestrel and levonorgestrel. However, only the levorotary enantiomer (levonorgestrel) is biologically active.
Metabolism
Not Available
Properties of Norgestrel
| Melting point: | 239-241 °C(lit.) |
| Boiling point: | 392.36°C (rough estimate) |
| Density | 1.0697 (rough estimate) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly, Sonicated), Dichloromethane (Slightly), Methanol (Slightly |
| form | neat |
| color | Crystals from diethyl ether-hexane |
Safety information for Norgestrel
| Signal word | Danger |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for Norgestrel
| InChIKey | WWYNJERNGUHSAO-XUDSTZEESA-N |
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