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HomeProduct name listNICOTINIC ACID MONONUCLEOTIDE

NICOTINIC ACID MONONUCLEOTIDE

  • CAS NO.:321-02-8
  • Empirical Formula: C11H14NO9P
  • Molecular Weight: 335.2
  • MDL number: MFCD00070358
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-28 23:16:16
NICOTINIC ACID MONONUCLEOTIDE Structural

What is NICOTINIC ACID MONONUCLEOTIDE?

The Uses of NICOTINIC ACID MONONUCLEOTIDE

A nucleotide of nicotinic acid which is produced from quinolinic acid by quinolinate phosphoribosyltransferase via transfer of a phosphoribose group. It is an intermediate of nicotinic acid adenine dinucleotide (NaAD) which is then converted to NAD via amidation and in turn converted to NADPH.

What are the applications of Application

Nicotinic acid mononucleotide is can be used to study the phosphate-responsive signaling pathway in yeast

Synthesis

Nicotinic acid mononucleotide is prepared by the reaction of 2,3-dicarboxypyridine and 5-phosphoribosyl-1-pyrophosphate. The steps are as follows:
With phosphoribosyl pyrophosphate-quinolinate phosphoribosyltransferase; magnesium chloride In aq. phosphate buffer at 37℃; for 6h; pH=7.0; Enzymatic reaction.
Nicotinic acid mononucleotide synthesis

Properties of NICOTINIC ACID MONONUCLEOTIDE

Melting point: >115°C (dec.)
storage temp.  −20°C
solubility  Methanol (Slightly, Heated), Water(Slightly)
form  Solid
color  White to Off-White
Stability: Hygroscopic
InChI InChI=1/C11H14NO9P/c13-8-7(5-20-22(17,18)19)21-10(9(8)14)12-3-1-2-6(4-12)11(15)16/h1-4,7-10,13-14H,5H2,(H2-,15,16,17,18,19)/t7-,8-,9-,10-/s3

Safety information for NICOTINIC ACID MONONUCLEOTIDE

Computed Descriptors for NICOTINIC ACID MONONUCLEOTIDE

InChIKey JOUIQRNQJGXQDC-NLNRFTKUNA-N
SMILES [C@@H]1([C@H](O)[C@H](O)[C@@H](COP([O-])(=O)O)O1)[N+]1C=CC=C(C(=O)O)C=1 |&1:0,1,3,5,r|

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