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HomeProduct name listMETHYLENEDIPHOSPHONIC ACID

METHYLENEDIPHOSPHONIC ACID

Synonym(s):MDP;Medronic acid;Methanediphosphonic acid, Medronic acid;Methylenediphosphonic acid

  • CAS NO.:1984-15-2
  • Empirical Formula: CH6O6P2
  • Molecular Weight: 176
  • MDL number: MFCD00002139
  • EINECS: 217-851-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-12-20 20:39:53
METHYLENEDIPHOSPHONIC ACID Structural

What is METHYLENEDIPHOSPHONIC ACID?

Chemical properties

Colourless solid

The Uses of METHYLENEDIPHOSPHONIC ACID

Radioactive imaging agent

The Uses of METHYLENEDIPHOSPHONIC ACID

Methylenediphosphonic acid is a radioactive compound used for skeletal imaging. MDP has been used as a chelating agent to vary calcium levels in cell culture in a study of caffeine storage in bovine chromaffin cells.

The Uses of METHYLENEDIPHOSPHONIC ACID

Methylenediphosphonic acid can be used as a precursor in the synthesis of:

  • Mesoporous aluminum organophosphonate in the presence of alkyltrimethylammonium as a surfactant.
  • Tetraester of methylenediphosphonic acids which are used as metal ion extractants for actinides in all oxidation states.

What are the applications of Application

Medronic Acid is a radioactive compound used for skeletal imaging

Definition

ChEBI: A 1,1-bis(phosphonic acid) consisting of methane substituted by two phosphonic acid groups.

General Description

MDP (Methylenediphosphonic acid) is a phosphonic analog of ATP.

Metabolism

Not Available

Properties of METHYLENEDIPHOSPHONIC ACID

Melting point: 197-199 °C(lit.)
Boiling point: 583.2±60.0 °C(Predicted)
Density  2.111±0.06 g/cm3(Predicted)
storage temp.  -20°C
solubility  DMSO : 250 mg/mL (1420.45 mM; Need ultrasonic)
form  Moist Crystals or Crystalline Powder
pka 1.43±0.10(Predicted)
color  Blue
Water Solubility  Soluble in water.
Merck  14,5792
BRN  1708494
CAS DataBase Reference 1984-15-2(CAS DataBase Reference)

Safety information for METHYLENEDIPHOSPHONIC ACID

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H314:Skin corrosion/irritation
Precautionary Statement Codes P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P363:Wash contaminated clothing before reuse.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for METHYLENEDIPHOSPHONIC ACID

InChIKey MBKDYNNUVRNNRF-UHFFFAOYSA-N

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