METHYLENEDIPHOSPHONIC ACID
Synonym(s):MDP;Medronic acid;Methanediphosphonic acid, Medronic acid;Methylenediphosphonic acid
- CAS NO.：1984-15-2
- Empirical Formula: CH6O6P2
- Molecular Weight: 176
- MDL number: MFCD00002139
- EINECS: 217-851-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-12-20 20:39:53
What is METHYLENEDIPHOSPHONIC ACID?
Chemical properties
Colourless solid
The Uses of METHYLENEDIPHOSPHONIC ACID
Radioactive imaging agent
The Uses of METHYLENEDIPHOSPHONIC ACID
Methylenediphosphonic acid is a radioactive compound used for skeletal imaging. MDP has been used as a chelating agent to vary calcium levels in cell culture in a study of caffeine storage in bovine chromaffin cells.
The Uses of METHYLENEDIPHOSPHONIC ACID
Methylenediphosphonic acid can be used as a precursor in the synthesis of:
- Mesoporous aluminum organophosphonate in the presence of alkyltrimethylammonium as a surfactant.
- Tetraester of methylenediphosphonic acids which are used as metal ion extractants for actinides in all oxidation states.
What are the applications of Application
Medronic Acid is a radioactive compound used for skeletal imaging
Definition
ChEBI: A 1,1-bis(phosphonic acid) consisting of methane substituted by two phosphonic acid groups.
General Description
MDP (Methylenediphosphonic acid) is a phosphonic analog of ATP.
Metabolism
Not Available
Properties of METHYLENEDIPHOSPHONIC ACID
| Melting point: | 197-199 °C(lit.) |
| Boiling point: | 583.2±60.0 °C(Predicted) |
| Density | 2.111±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO : 250 mg/mL (1420.45 mM; Need ultrasonic) |
| form | Moist Crystals or Crystalline Powder |
| pka | 1.43±0.10(Predicted) |
| color | Blue |
| Water Solubility | Soluble in water. |
| Merck | 14,5792 |
| BRN | 1708494 |
| CAS DataBase Reference | 1984-15-2(CAS DataBase Reference) |
Safety information for METHYLENEDIPHOSPHONIC ACID
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for METHYLENEDIPHOSPHONIC ACID
| InChIKey | MBKDYNNUVRNNRF-UHFFFAOYSA-N |
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