Nickel(II) chloride hexahydrate

Chemical properties

Green solid

The Uses of Nickel(II) chloride hexahydrate

Nickel(II) chloride hexahydrate has been used:

• in the preparation of nickel platting solution for galvanostatically coating nickel inside the reduced carbon layer during the synthesis of multiwall carbon nanotube micromotors
• in screening of metals for inflammatory effect on vascular endothelial cells
• as an additive in artificial cerebrospinal fluid (ACSF) to analyse excitatory post synaptic currents (EPSPs) in the hippocampus slices

The Uses of Nickel(II) chloride hexahydrate

Anhydr salt as absorbent for NH3 in gas masks. Hexahydrate for nickel electroplating; manufacture of nickel catalysts.

The Uses of Nickel(II) chloride hexahydrate

Nickel(II) chloride hexahydrate may be employed as a catalyst in the high yield synthesis of tetra-substituted pyrrole derivatives. It may be used for the conversion of tetrahydropyranyl (THP) and tert-butyldimethylsilyl (TBS) ethers to the corresponding hydroxyl compounds.

What are the applications of Application

Nickel(II) chloride hexahydrate is a reagent used in electroplating and in gas masks to absorb NH3

Definition

ChEBI: A hydrate of nickel chloride containing nickel (in the +2 oxidation state), chloride and water moeities in the ratio 1:2:6.

General Description

Nickel(II) chloride hexahydrate is a nickel salt that can be used as a catalyst. It is cost effective and can be used in a variety of industrial processes. It can also be used in cross-coupling reactions.

Hazard

Confirmed carcinogen.

Biochem/physiol Actions

Nickel (Ni) is an essential trace element that plays an important role in the structure and function of DNA, RNA and protein. It has toxic effects on renal, pulmonary and cardiovascular system at higher concentrations. Nickel is implicated in carcinogenesis. Ni2+ ions is a clastogenic agent. Nickel ions (Ni2+) is a non-specific voltage-gated calcium channel blocker.

Safety Profile

Confirmed human carcinogen. Poison by intraperitoneal and intravenous routes. Experimental reproductive effects. Mutation data reported. Violent reaction with potassium. When heated to decomposition it emits very toxic fumes of Cl-. See also NICKEL COMPOUNDS and CHLORIDES.

Purification Methods

It crystallises from dilute HCl to form the green hexahydrate. At 70o this dehydrates to the tetrahydrate, and at higher temperatures it forms the anhydrous salt. It sublimes in yellow hexagonal scales in a stream of HCl. Store it in a desiccator as it is deliquescent. [Hart & Partington J Chem Soc 104 1943.]