N-Octyl pyrrolidone
- CAS NO.：2687-94-7
- Empirical Formula: C12H23NO
- Molecular Weight: 197.32
- MDL number: MFCD00074965
- EINECS: 403-700-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-01 18:09:03
What is N-Octyl pyrrolidone ?
Chemical properties
Colorless or slightly yellow clear liquid
The Uses of N-Octyl pyrrolidone
N-Octyl pyrrolidone(NOP) is a highly efficient and selective solvent, which can be used in the recovery of organic raw materials, the refining of lubricating oils, and the solvent for polymers and polymerization reactions; It is also widely used in chemical synthesis reactions.
Definition
ChEBI: N-Octyl-2-pyrrolidone is a N-alkylpyrrolidine.
Synthesis Reference(s)
The Journal of Organic Chemistry, 57, p. 3328, 1992 DOI: 10.1021/jo00038a019
Synthesis Reference(s)
The Journal of Organic Chemistry, 59, p. 6378, 1994 DOI: 10.1021/jo00100a046
General Description
1-Octyl-2-pyrrolidone is a permeation enhancer and its effect in transport of steroidal permeants across hairless mouse skin was investigated via a parallel pathway skin model.
Flammability and Explosibility
Non flammable
Safety Profile
Moderately toxic by ingestion. Asevere skin and eye irritant. A corrosive. Combustibleliquid. When heated to decomposition it emits toxic fumesof NOx.
Properties of N-Octyl pyrrolidone
| Melting point: | −25 °C(lit.) |
| Boiling point: | 170-172 °C15 mm Hg(lit.) |
| Density | 0.92 g/mL at 25 °C(lit.) |
| vapor pressure | 0.03-0.08Pa at 20℃ |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| form | clear liquid |
| pka | -0.42±0.20(Predicted) |
| Specific Gravity | 0.92 |
| color | Colorless to Yellow |
| Water Solubility | 1.14-1.25g/L at 20℃ |
| BRN | 1526318 |
| CAS DataBase Reference | 2687-94-7(CAS DataBase Reference) |
| EPA Substance Registry System | N-Octyl-2-pyrrolidone (2687-94-7) |
Safety information for N-Octyl pyrrolidone
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Environment GHS09 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation H411:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N-Octyl pyrrolidone
| InChIKey | WPPOGHDFAVQKLN-UHFFFAOYSA-N |
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