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HomeProduct name listN-Chlorophthalimide

N-Chlorophthalimide

  • CAS NO.:3481-09-2
  • Empirical Formula: C8H4ClNO2
  • Molecular Weight: 181.58
  • MDL number: MFCD00023027
  • EINECS: 222-459-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-24 19:19:26
N-Chlorophthalimide Structural

What is N-Chlorophthalimide?

Chemical properties

White to pale yellow powder

The Uses of N-Chlorophthalimide

N-Chlorophthalimide may be employed in the synthesis of:

  • α-amino acetal
  • α-amino nitro compounds
  • vicinal diamine
  • α,β-unsaturated vicinal haloamino nitro compound
It may also be used as a chlorination reagent for the synthesis of 3-(methylthio)oxindoles.

General Description

N-Chlorophthalimide in anhydrous acetic acid serves as a useful oxidizing reagent for use in various direct titrimetric analyses. N-Chlorophthalimide can be synthesized by reacting phthalimide, t-butyl hypochlorite, water and t-butyl alcohol. It participates in the synthesis of 2-amino-3-benzoyl-α-(methylthio)phenylacetamide.

Properties of N-Chlorophthalimide

Melting point: 188-198 °C (lit.)
Boiling point: 315.1±25.0 °C(Predicted)
Density  1.56±0.1 g/cm3(Predicted)
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
form  powder to crystal
pka -3.53±0.20(Predicted)
color  White to Almost white
CAS DataBase Reference 3481-09-2(CAS DataBase Reference)

Safety information for N-Chlorophthalimide

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for N-Chlorophthalimide

InChIKey WDRFYIPWHMGQPN-UHFFFAOYSA-N

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