N-BOC-4-Hydroxypiperidine
Synonym(s):tert-Butyl 4-hydroxy-1-piperidinecarboxylate;1-Boc-4-piperidinol
- CAS NO.:109384-19-2
- Empirical Formula: C10H19NO3
- Molecular Weight: 201.26
- MDL number: MFCD01075174
- EINECS: 600-916-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-06-25 20:17:06
What is N-BOC-4-Hydroxypiperidine?
Chemical properties
White to cream powder
The Uses of N-BOC-4-Hydroxypiperidine
N-Boc-4-hydroxypiperidine is a 4-hydroxypyridine with a boc protecting group used in the preparation of neurologically active agents and other pharmaceutical compounds.
The Uses of N-BOC-4-Hydroxypiperidine
Used in a synthesis of N-heterocyclic alkyl ethers via the Mitsunobu reaction.
Preparation
A mixture of 4-hydroxypiperidine (10.0 g, 98. 9 mmol), aqueous sodiumhydrogen carbonate (150 mL, 1 M), DI-FERT-BUTYL dicarbonate (21. 6 g, 98.9 mmol) and dichloromethane was stirred for 15 h. The phases were separated and the product (N-BOC-4-Hydroxypiperidine) was isolated as an oil in quantitative yield (19.9 g).
Properties of N-BOC-4-Hydroxypiperidine
Melting point: | 61-65 °C (lit.) |
Boiling point: | 292.3±33.0 °C(Predicted) |
Density | 1.107±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | Chloroform, Ethyl Acetate |
form | Powder |
pka | 14.80±0.20(Predicted) |
color | White to cream |
BRN | 7202094 |
InChI | InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-8(12)5-7-11/h8,12H,4-7H2,1-3H3 |
CAS DataBase Reference | 109384-19-2(CAS DataBase Reference) |
Safety information for N-BOC-4-Hydroxypiperidine
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N-BOC-4-Hydroxypiperidine
InChIKey | PWQLFIKTGRINFF-UHFFFAOYSA-N |
SMILES | N1(C(OC(C)(C)C)=O)CCC(O)CC1 |
Abamectin manufacturer
BTC pharm India
3Y
Phone:+91-8790379245
Whatsapp: +91- 8790379245
product: N-BOC-4-Hydroxypiperidine 98+
TAGOOR LABORATORIES PVT LTD
2Y
Phone:+91-9505502670
Whatsapp: +91- 9505502670
product: 109384-19-2 N-BOC-4-hydroxypiperidine >98%
SYNARTIS PHARMA PVT LTD
2Y
Phone:+91-9949688280
Whatsapp: +91- 9949688280
product: 1-Boc-4-hydroxypiperidine NLT-98%
Ganapa Life Science Pvt. Ltd.,
1Y
Phone:+91-9480037951
Whatsapp: +91 7760536535
product: Tert-butyl 4-hydroxypiperidine-1-carboxylate 109384-19-2 99%
JIVICHEM SYNTHESIS PVT LTD
1Y
Phone:+91-7028392790
Whatsapp: +91 7028392790
product: 109384-19-2 N-(tert-Butoxycarbonyl)-4-piperidinol 98%
REDDY N REDDY PHARMACEUTICALS
1Y
Phone:+91-9848096759
Whatsapp: +91 9848096759
product: 109384-19-2 1-boc-4-hydroxy piperidine 98%
JSK Chemicals
1Y
Phone:+91 9879767970;+919879767970
Whatsapp: +91 9879767970
product: 109384-19-2 99%
New Products
2,2-diethoxyethanethioamide (R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin G Tubulysin I 3-Aminocyclobutanone hydrochloride 2H-Pyran, 4-ethynyltetrahydro- 4,4-DIFLUOROPIPERIDINE 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) tetrahydro-4-methyl-2H-pyran 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE Fuel shell 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Imeglimin Hydrochloride IH Calcium Sodium Phosphosilicate IH 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 1-Aminoindan Hydrochloride (3-Fluoro-4- morpholin-4-yl- phenyl)- carbamic acid methyl ester Magnesium Trisilicate Latanoprostene Bunod Lubiprostone Flame Retardant Zinc Borate 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carbonitrileRelated products of tetrahydrofuran
1-Boc-4-cyanopiperidine
N-Boc-4-piperidinemethanol
tert-Butyl 4-methylenepiperidine-1-carboxylate
1-Boc-3-piperidone
4-Hydroxypiperidine
Triacetonediamine
tert-Butyl peroxyacetate
N-Carbobenzyloxyglycine
You may like
-
N-Boc-4-hydro xypiperidine 98%View Details
109384-19-2 -
109384-19-2 98%View Details
109384-19-2 -
N-BOC-4-Hydroxypiperidine 98+View Details
109384-19-2 -
1-(tert-Butoxycarbonyl)-4-hydroxypiperidine CAS 109384-19-2View Details
109384-19-2 -
1-Boc-4-hydroxypiperidine, 97% CAS 109384-19-2View Details
109384-19-2 -
1-Boc-4-hydroxypiperidine CAS 109384-19-2View Details
109384-19-2 -
tert-Butyl 4-hydroxypiperidine-1-carboxylate 99% CAS 109384-19-2View Details
109384-19-2 -
N-Boc-4-Hydroxylpiperidine 99% (GC) CAS 109384-19-2View Details
109384-19-2
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.