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HomeProduct name list4-Hydroxypiperidine

4-Hydroxypiperidine

Synonym(s):4-Piperidinol

  • CAS NO.:5382-16-1
  • Empirical Formula: C5H11NO
  • Molecular Weight: 101.15
  • MDL number: MFCD00005999
  • EINECS: 226-373-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
4-Hydroxypiperidine  Structural

What is 4-Hydroxypiperidine ?

Chemical properties

yellow to yellow-orange wet solid

The Uses of 4-Hydroxypiperidine

4-Hydroxypiperidine is used as a reagent for the synthesis of acridine (A190900) derivatives and fibrinogen receptor antagonists.

The Uses of 4-Hydroxypiperidine

4-Hydroxypiperidine (4-Piperidinol) can be used in the synthesis of a highly potent and selective IP (PGI(2) receptor) agonist. It can also be used in the study of copper-catalyzed N- versus O-arylation.

General Description

The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H(3) receptor.

Flammability and Explosibility

Not classified

Properties of 4-Hydroxypiperidine

Melting point: 86-90 °C
Boiling point: 108-114 °C/10 mmHg (lit.)
Density  0.9903 (rough estimate)
vapor pressure  13Pa at 25℃
refractive index  1.4400 (estimate)
Flash point: 226 °F
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Solid
pka 14.94±0.20(Predicted)
color  Off-White to pale Yellow
PH 11.5-11.7 (H2O)Aqueous solution
Water Solubility  soluble
Sensitive  Hygroscopic
BRN  102738
CAS DataBase Reference 5382-16-1(CAS DataBase Reference)
NIST Chemistry Reference 4-Hydroxypiperidine(5382-16-1)

Safety information for 4-Hydroxypiperidine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for 4-Hydroxypiperidine

InChIKey HDOWRFHMPULYOA-UHFFFAOYSA-N

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