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HomeProduct name listN-Acetyl-DL-phenylalanine

N-Acetyl-DL-phenylalanine

  • CAS NO.:2901-75-9
  • Empirical Formula: C11H13NO3
  • Molecular Weight: 207.23
  • MDL number: MFCD00063157
  • EINECS: 220-793-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-05-28 19:59:05
N-Acetyl-DL-phenylalanine Structural

What is N-Acetyl-DL-phenylalanine?

Originator

Afalanine ,Sankyo

The Uses of N-Acetyl-DL-phenylalanine

N-Acetyl-DL-phenylalanine is an antidepressant, used to prevent kidney damage.

Definition

ChEBI: The N-acetyl derivative of phenylalanine.

Manufacturing Process

The phenylalanine was dispersed in water. A 1 N aqueous solution of sodium hydroxide was slowly added to this dispersion, and the pH of the solution reached a value of 7-8.
Then acetylbromide was dissolved in this solution, to give a Nacetylphenylalanine.

Therapeutic Function

Antidepressant

Synthesis Reference(s)

Tetrahedron Letters, 31, p. 243, 1990 DOI: 10.1016/S0040-4039(00)94382-X

Properties of N-Acetyl-DL-phenylalanine

Melting point: 152.0 to 156.0 °C
Boiling point: 453.9±38.0 °C(Predicted)
Density  1.199±0.06 g/cm3(Predicted)
RTECS  SQ7321132
storage temp.  Inert atmosphere,Store in freezer, under -20°C
form  Powder
pka 3.56±0.10(Predicted)
color  Off-white
λmax 280nm(lit.)
CAS DataBase Reference 2901-75-9(CAS DataBase Reference)

Safety information for N-Acetyl-DL-phenylalanine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for N-Acetyl-DL-phenylalanine

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