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HomeProduct name listMethyl (R)-(+)-lactate

Methyl (R)-(+)-lactate

Synonym(s):D-Lactic acid methyl ester;Methyl (R)-(+)-lactate

  • CAS NO.:17392-83-5
  • Empirical Formula: C4H8O3
  • Molecular Weight: 104.1
  • MDL number: MFCD00004517
  • EINECS: 241-420-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-11-15 17:17:25
Methyl (R)-(+)-lactate Structural

What is Methyl (R)-(+)-lactate?

Chemical properties

Colorless to light yellow liqui

The Uses of Methyl (R)-(+)-lactate

(+)-Methyl D-lactate can be used as a starting material in the asymmetric preparation of:

  • Neomethymycin, a macrolide which contains 12-membered macrolactone that is used as a potent biological agent.
  • PM-toxin A.

It can also be used as a chiral pool along with D-(-)-tartaric acid in the stereoselective total synthesis of separacenes A and B via Trost-Rychnovsky alkyne rearrangement, Horner-Wadsworth-Emmons olefination as well as Corey-Bakshi-Shibata reaction.

Definition

ChEBI: A methyl lactate that has R configuration.

General Description

This compound has benign qualities and is biodegradable, water miscible, and functions as a versatile solvent for CA membrane preparation. This is also used as an intermediate for the production of other chemicals, polymers, and derivatives. Thus this product has been enhanced for Safer solvents and auxiliaries.

Properties of Methyl (R)-(+)-lactate

Boiling point: 144-145 °C(lit.)
alpha  8.5 º (c=neat)
Density  1.09 g/mL at 25 °C(lit.)
refractive index  n20/D 1.413(lit.)
Flash point: 121 °F
storage temp.  Inert atmosphere,2-8°C
solubility  Chloroform, Ethyl Acetate (Slightly), Methanol (Slightly)
pka 13.07±0.20(Predicted)
form  Liquid
color  Clear colorless
optical activity [α]21/D +8.4°, neat
Water Solubility  miscible, hydrolyses
Merck  14,6094
CAS DataBase Reference 17392-83-5(CAS DataBase Reference)

Safety information for Methyl (R)-(+)-lactate

Signal word Warning
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H226:Flammable liquids
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Methyl (R)-(+)-lactate

InChIKey LPEKGGXMPWTOCB-GSVOUGTGSA-N

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