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HomeProduct name listMethyl lactate

Methyl lactate

  • CAS NO.:547-64-8
  • Empirical Formula: C4H8O3
  • Molecular Weight: 104.1
  • MDL number: MFCD00066367
  • EINECS: 208-930-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-21 22:41:43
Methyl lactate Structural

What is Methyl lactate?

Chemical properties

Methyl lactate is a colorless transparent liquid. It is soluble/miscible in water, acetone, ethyl alcohol, and other organic solvents. It is used as a cellulose acetate solvent.

The Uses of Methyl lactate

Methyl lactate is used as a solvent for nitrocellulose, cellulase acetate, cellulase acetobutyrote and cellulase acetaprapionate. It is used in the manufacture of lacquers and dopes where it contributes high tolerance for diluents, good flaw and blush resistance.

Definition

ChEBI: Methyl lactate is a lactate ester resulting from the formal condensation of the carboxy group of 2-hydroxypropanoic acid with methanol. It has a role as a metabolite. It is a lactate ester and a methyl ester.

Hazard

Moderate fire risk.

Safety Profile

Methyl lactate has been classed as non-irritant to the eyes of guinea pigs.
The estimated average lethal dose for the female rat following i.p. injection of methyl lactate was >2000 mg/kg body weight. Observations included narcosis, respiratory distress and peritoneal adhesions. The estimated non toxic dose and estimated maximum dose without gross lesions at necropsy was 500 mg/kg body weight.

Synthesis

Methyl lactate is prepared by the esterification of methyl alcohol with lactic acid.

Purification Methods

Methyl lactate is easily hydrolyzed and often contains impurities such as free lactic acid, methanol and water. Free acid can be removed by washing after neutralization with alkali. Moisture can be removed by azeotropic distillation of an azeotropic mixture with benzene. Then, it was purified by distillation under reduced pressure. Since calcium chloride and the like form molecular compounds with methyl lactate, they cannot be used as desiccants. When the methyl lactate is mixed with water, it can be extracted and recovered with benzene, ether, etc.

Properties of Methyl lactate

Melting point: -66°C
Boiling point: 35 °C (6 mmHg)
alpha  [α]D20+1.410~+1.418
Density  1.093 g/mL at 20 °C(lit.)
refractive index  n20/D 1.413
Flash point: 49 °C
storage temp.  Flammables area
form  Liquid
pka 13.07±0.20(Predicted)
Specific Gravity 1.09
color  Clear colorless to pale yellow
Water Solubility  miscible, hydrolyses
Sensitive  Moisture Sensitive
Merck  14,6094
BRN  1720586
CAS DataBase Reference 547-64-8(CAS DataBase Reference)
NIST Chemistry Reference Propanoic acid, 2-hydroxy-, methyl ester(547-64-8)
EPA Substance Registry System Methyl lactate (547-64-8)

Safety information for Methyl lactate

Signal word Warning
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H226:Flammable liquids
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233:Keep container tightly closed.
P240:Ground/bond container and receiving equipment.
P241:Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242:Use only non-sparking tools.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Methyl lactate

InChIKey LPEKGGXMPWTOCB-UHFFFAOYSA-N

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