Cinnamoyl chloride

Synonym(s):trans-3-Phenylacryloyl chloride;Cinnamic acid chloride;Cinnamoyl chloride

CAS NO.：102-92-1
Empirical Formula: C9H7ClO
Molecular Weight: 166.6
MDL number: MFCD00000732
EINECS: 203-065-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-24 19:19:26

What is Cinnamoyl chloride?

Chemical properties

white to yellowish crystalline solid

The Uses of Cinnamoyl chloride

Titrimetric determination of small amounts of water.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 3, p. 714, 1955
Tetrahedron Letters, 14, p. 5121, 1973 DOI: 10.1016/S0040-4039(01)87403-7

Hazard

Skin irritant.

Purification Methods

Refractionate it in a vacuum until the distillate solidifies on cooling, and recrystallise it from pet ether. The trans-amide has m 145-150o (from H2O) [Beilstein 9 III 2711]. [Adams & Ulich J Am Chem Soc 42 605 1920, Bergmann et al. J Chem Soc 2524 1952, Beilstein 9 H 587, 9 I 233, 9 II 390, 9 III 2710, 9 IV 2020.]

Properties of Cinnamoyl chloride

Melting point:	35-37 °C (lit.)
Boiling point:	256-258 °C (lit.)
Density	d445.3 1.1617
refractive index	nD42.5 1.614
Flash point:	>230 °F
storage temp.	2-8°C
solubility	dioxane: 0.1 g/mL, clear
form	Crystalline Solid
color	White to yellow
Water Solubility	DECOMPOSES
Merck	13,2323
BRN	606265
CAS DataBase Reference	102-92-1(CAS DataBase Reference)
NIST Chemistry Reference	2-Propenoyl chloride, 3-phenyl-(102-92-1)
EPA Substance Registry System	2-Propenoyl chloride, 3-phenyl- (102-92-1)

Safety information for Cinnamoyl chloride

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.