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HomeProduct name listLY 2784544

LY 2784544

Synonym(s):3-(4-Chloro-2-fluorobenzyl)-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(morpholinomethyl)imidazo[1,2-b]pyridazin-6-amine;3-[(4-Chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(4-morpholinylmethyl)imidazo[1,2-b]pyridazin-6-amine;LY 2784544;LY-2784544

LY 2784544 Structural

What is LY 2784544?

The Uses of LY 2784544

LY2784544 is a JAK2 inhibitor. LY2784544 may be used as a potential treatment for patients with myeloproliferative neoplasm.

What are the applications of Application

LY2784544 is a selective inhibitor of JAK2 mutant V617F

Definition

ChEBI: Gandotinib is a member of pyridazines.

Properties of LY 2784544

Density  1.45
storage temp.  Store at -20°C
solubility  ≥23.5 mg/mL in DMSO; insoluble in H2O; ≥5.65 mg/mL in EtOH with gentle warming and ultrasonic
form  solid
pka 14.12±0.10(Predicted)
color  Light yellow to yellow

Safety information for LY 2784544

Computed Descriptors for LY 2784544

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