Lapatinib Ditosylate
- CAS NO.：388082-77-7
- Empirical Formula: C36H34ClFN4O7S2
- Molecular Weight: 753.26
- MDL number: MFCD09264195
- EINECS: 1312995-182-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-09-07 14:58:50
What is Lapatinib Ditosylate?
Description
Lapatinib, an ErB-1 and ErB-2 dual kinase inhibitor, was launched for the treatment of advanced or metastatic HER2 (ErbB2) positive breast cancer in women who have received prior therapy. The drug was discovered and developed by GlaxoSmithKline and is also currently being evaluated for several additional cancer indications.
The Uses of Lapatinib Ditosylate
Lapatinib Ditosylate (GW572016, GW2016, Tykerb, Tyverb) is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively.
Properties of Lapatinib Ditosylate
| Melting point: | 240-2420C |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | ≥24.3 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O |
| form | solid |
| Water Solubility | Water: Insoluble |
Safety information for Lapatinib Ditosylate
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H225:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P370+P378:In case of fire: Use … for extinction. P403+P235:Store in a well-ventilated place. Keep cool. |
Computed Descriptors for Lapatinib Ditosylate
Abamectin manufacturer
Dodhia Group
1Y
Phone:+91-9619867345
Whatsapp: +91 9619867345
product: Lapatinib Ditosylate Anhydrous 99%
Vannsh Life Sciences Pvt Ltd
1Y
Phone:+91-9642555246
Whatsapp: +91-9642555246
product: 388082-77-7 99%
Salvavidas Pharmaceutical Pvt., Ltd.
1Y
Phone:+91-9327127459
Whatsapp: +91 9327127459
product: Lapatinib Ditosylate Anhydrous 98%
Basil Drugs AND Pharmaceuticals Pvt Ltd
1Y
Phone:+91-9619320820
Whatsapp: +91 9619320820
product: Lapatinib Ditosylate Anhydrous 388082-77-7 98%
Kekule Pharma Limited
1Y
Phone:+919849798889
Whatsapp: +91 9849798889
product: 388082-77-7 Lapatinib Ditosylate Anhydrous 98%
Sumar Biotech LLP
1Y
Phone:+91-9824575381
Whatsapp: +91-9824575381
product: Lapatinib Ditosylate Anhydrous 98%
Beta Drugs
1Y
Phone:+91-7015991921
Whatsapp: +91-7015991921
product: Lapatinib Ditosylate Anhydrous 388082-77-7 98%
Aspen Biopharma Labs Pvt Ltd
1Y
Phone:+91-9248058662
Whatsapp: +91-9248058662
product: 388082-77-7 98%
New Products
3-N-BOC-(S)-AMINO BUTYRONITRILE 4-Piperidinopiperidine 2-Methyl-4-nitrobenzoic acid 2-(4-bromophenyl)-2-methylpropanoic acid 4-Acetyl-2-methylbenzoicacid Acetyl-meldrum's acid Ethyl-4-Pyrazole carboxylate 2,6 Di acetylpyridine 2,6-Pyridinedimethanol 5,7-Dichloro-3H-Imidazo[4,5-B]Pyridine 5-Bromo-2-Methoxy-4-Methyl-3-Nitropyridine 2-Fluoro-5-Iodopyridine 2-Fluoro-5-Methylpyridine 2-Chloro-3-Bromo-5-Amiopyridine METHYL-4-(BUTYRYLAMINO)3-METHYL-5-NITROBENZOATE TRANS-CYCLOBUTANE-1,2- DICARBOXYLIC ACID 5-Nitro indazole R-(-)-5-(2-AMINO-PROPYL)-2-METHOXY-BENZENESULFONAMIDE 1,3-cyclohexanedione 4-Aminophenaethylalchol (S)-(+)-4-BENZYL-2-OXAZOLIDINONE 3-NITRO-5-ACETYL IMINODIBENZYL 1-HYDROXY-4-METHYL6-(2,4,4-TRI METHYL PHENYL)-2-PYRIDONE MONO ETHANOL AMINE(PIROCTONE OLAMINE) 4-FLUORO PHENYL MAGNESIUM BROMIDE 1.0 M IN THFRelated products of tetrahydrofuran
You may like
-
Lapatinib Ditosylate Anhydrous 99%View Details -
Lapatinib Ditosylate Anhydrous 98%View Details
388082-77-7 -
Lapatinib Ditosylate Anhydrous 388082-77-7 98%View Details
388082-77-7 -
388082-77-7 Lapatinib Ditosylate Anhydrous 98%View Details
388082-77-7 -
388082-77-7 98%View Details
388082-77-7 -
Lapatinib Ditosylate Anhydrous 98%View Details
388082-77-7 -
388082-77-7 98%View Details
388082-77-7 -
388082-77-7 Lapatinib Ditosylate Anhydrous 99%View Details
388082-77-7
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.