L-tert-Leucine

Synonym(s):(S)-2-Amino-3,3-dimethylbutyric acid;(S)-2-Amino-4-methylpentanoic acid;L-α-tert-Butylglycine;L-Leucine

CAS NO.：20859-02-3
Empirical Formula: C6H13NO2
Molecular Weight: 131.17
MDL number: MFCD00064218
EINECS: 424-750-7
SAFETY DATA SHEET (SDS)
Update Date: 2025-01-27 09:38:02

What is L-tert-Leucine?

Chemical properties

White to almost white powder

The Uses of L-tert-Leucine

L-tert-Leucine is an essential amino acid and makes up one third of our muscle protein. It can be used as a food additive. It is used in the formation of sterols. It is used in the production of cobalt oxazoline palladacycles complex, which acts as a catalyst in the rearrangement of prochiral N-aryl trifluoroacetimidates to allylic amides yielded in significantly higher enantioselectivities with the (S)-(pR)-diasteroisomer.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 3, p. 523, 1955
Tetrahedron Letters, 19, p. 4625, 1978 DOI: 10.1016/S0040-4039(01)85688-4

Properties of L-tert-Leucine

Melting point:	≥300 °C (lit.)
Boiling point:	217.7±23.0 °C(Predicted)
alpha	6.3 º (c=4, 6 N HCl 200 ºC)
Density	1.1720 (estimate)
refractive index	-9 ° (C=3, H2O)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	1 M HCl: 50 mg/mL
form	powder
pka	2.39±0.12(Predicted)
color	White to almost white
optical activity	[α]20/D 9.5°, c = 3 in H2O
Water Solubility	125.5 g/L (20 ºC)
BRN	1721824
CAS DataBase Reference	20859-02-3(CAS DataBase Reference)

Safety information for L-tert-Leucine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P362:Take off contaminated clothing and wash before reuse. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention.