IODOACETIC ACID SODIUM SALT
Synonym(s):Iodoacetic acid sodium salt;Iodoacetic Acid, Sodium Salt - CAS 305-53-3 - Calbiochem
- CAS NO.：305-53-3
- Empirical Formula: C2H2INaO2
- Molecular Weight: 207.93
- MDL number: MFCD00002686
- EINECS: 206-165-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:08:57
What is IODOACETIC ACID SODIUM SALT?
Chemical properties
light yellow to yellow-brown powder
The Uses of IODOACETIC ACID SODIUM SALT
Analytical reagent.
The Uses of IODOACETIC ACID SODIUM SALT
Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.
What are the applications of Application
Iodoacetic acid sodium salt is a reagent used to modify cysteine residues in proteins to inhibit cysteine proteases.
Hazard
Toxic.
Biochem/physiol Actions
Used to induce osteoarthritis-like lesions and functional impairment in rats, for testing of chondroprotective agents and diagnostic imaging techniques.
Safety Profile
Poison by ingestion and intraperitoneal routes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of Iand Na2O.
Properties of IODOACETIC ACID SODIUM SALT
| Melting point: | 208 °C (dec.)(lit.) |
| storage temp. | -20°C |
| solubility | methanol: 0.1 M at 20 °C, clear, colorless |
| form | Powder |
| color | Light yellow to yellow-brown |
| BRN | 4009322 |
| CAS DataBase Reference | 305-53-3(CAS DataBase Reference) |
| EPA Substance Registry System | Acetic acid, iodo-, sodium salt (305-53-3) |
Safety information for IODOACETIC ACID SODIUM SALT
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for IODOACETIC ACID SODIUM SALT
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