IODOACETIC ACID SODIUM SALT

Synonym(s):Iodoacetic acid sodium salt;Iodoacetic Acid, Sodium Salt - CAS 305-53-3 - Calbiochem

CAS NO.：305-53-3
Empirical Formula: C2H2INaO2
Molecular Weight: 207.93
MDL number: MFCD00002686
EINECS: 206-165-7
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-24 21:11:45

What is IODOACETIC ACID SODIUM SALT?

Chemical properties

light yellow to yellow-brown powder

The Uses of IODOACETIC ACID SODIUM SALT

Analytical reagent.

The Uses of IODOACETIC ACID SODIUM SALT

Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.

What are the applications of Application

Iodoacetic acid sodium salt is a reagent used to modify cysteine residues in proteins to inhibit cysteine proteases.

Hazard

Toxic.

Biochem/physiol Actions

Used to induce osteoarthritis-like lesions and functional impairment in rats, for testing of chondroprotective agents and diagnostic imaging techniques.

Safety Profile

Poison by ingestion and intraperitoneal routes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of Iand Na2O.

Properties of IODOACETIC ACID SODIUM SALT

Melting point:	208 °C (dec.)(lit.)
storage temp.	-20°C
solubility	methanol: 0.1 M at 20 °C, clear, colorless
form	Powder
color	Light yellow to yellow-brown
BRN	4009322
CAS DataBase Reference	305-53-3(CAS DataBase Reference)
EPA Substance Registry System	Acetic acid, iodo-, sodium salt (305-53-3)

Safety information for IODOACETIC ACID SODIUM SALT

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H301:Acute toxicity,oral H314:Skin corrosion/irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.