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HomeProduct name listHh-Ag 1.3

Hh-Ag 1.3

Synonym(s):Smoothened Agonist, SAG - CAS 364590-63-6 - Calbiochem

Hh-Ag 1.3 Structural

What is Hh-Ag 1.3?

The Uses of Hh-Ag 1.3

Smoothened Agonist, HCl (SAG), is a highly potent activator of Smo (smoothened). This chlorobenzothiophene compound is a hedgehog pathway agonist that interacts with the heptahelical domain of Smo. SAG is shown to act as an activator at low concentrations, but can inhibit Smo coupling at very high concentrations. The activating effects of SAG will counteract Cyclopamine or Cyclopamine-KAAD inhibition of Smo.

What are the applications of Application

Smoothened Agonist, HCl is a Hh pathway agonist that interacts with the heptahelical domain of Smo

Properties of Hh-Ag 1.3

Boiling point: 688.6±55.0 °C(Predicted)
Density  1.30±0.1 g/cm3(Predicted)
pka 10?+-.0.40(Predicted)
form  White to off-white solid.
Water Solubility  Soluble in water.
Sensitive  Light Sensitive & Hygroscopic

Safety information for Hh-Ag 1.3

Computed Descriptors for Hh-Ag 1.3

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