Glycitein
Synonym(s):4′,7-Dihydroxy-6-methoxyisoflavone;Glycetein
- CAS NO.:40957-83-3
- Empirical Formula: C16H12O5
- Molecular Weight: 284.26
- MDL number: MFCD00016679
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-05 08:26:49
What is Glycitein?
Description
Glycitein is an O-
Chemical properties
Pale Orange Solid
The Uses of Glycitein
Glycitein may be used as a reference standard in the determination of glycitein in hydrolyzed dry soya extracts using reversed-phase high-performance liquid chromatography (RP-HPLC).
The Uses of Glycitein
The compund shows an anti-cancer activity, plasma cholesterol reduction, reduction in postmenopausal bone loss
The Uses of Glycitein
Glycitein has been used as standard for the analysis of soy isoflavones and metabolites in urine. It has also been used to bind to recombinant estrogen and progesterone receptors to know the relative binding affinity (RBA) for detection of potential endocrine disruptors.
What are the applications of Application
Glycitein is a soybean isoflavonoid
Definition
ChEBI: A methoxyisoflavone that is isoflavone substituted by a methoxy group at position 6 and hydroxy groups at positions 7 and 4'. It has been isolated from the mycelia of the fungus Cordyceps sinensis.
General Description
Glycitein is an isoflavone found in soy food products.
Biochem/physiol Actions
Glycitein is a soybean (yellow cultivar) isoflavonoid; its natural glycosides are synergistic with genistein in inducing specific gene expression. Glycitein may be used to study anti-oxidation processes at the level of gene transcription where it increases the binding of transcription factors [nuclear factor-E2-related factor 2 (Nrf2) and c-Jun] to the antioxidant response element (ARE) on HO-1 and NQO1 promoters. Glycitein may be used in combination with other isoflavonoids such as genistein and daidzein to study apoptosis.
Properties of Glycitein
Melting point: | >300°C |
Boiling point: | 547.4±50.0 °C(Predicted) |
Density | 1.420±0.06 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | Aqueous Base (Slightly), DMSO (Slightly) |
form | Solid |
pka | 7.03±0.20(Predicted) |
color | Light Brown |
CAS DataBase Reference | 40957-83-3(CAS DataBase Reference) |
Safety information for Glycitein
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H301:Acute toxicity,oral H311:Acute toxicity,dermal H314:Skin corrosion/irritation H331:Acute toxicity,inhalation |
Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P302+P352:IF ON SKIN: wash with plenty of soap and water. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for Glycitein
InChIKey | DXYUAIFZCFRPTH-UHFFFAOYSA-N |
Abamectin manufacturer
CHROMOSYNTH PVT LTD
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