Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
- CAS NO.：161797-99-5
- Empirical Formula: C13H13NO3S
- Molecular Weight: 263.31
- MDL number: MFCD03700424
- EINECS: 605-268-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-13 18:00:15
What is Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate?
The Uses of Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate is used in the synthesis of the major metabolites of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.
Properties of Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
| Melting point: | 180 ºC |
| Boiling point: | 426.8±55.0 °C(Predicted) |
| Density | 1.274 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Very Slightly) |
| form | Solid |
| color | Off-White |
Safety information for Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
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