Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
- CAS NO.:161798-01-2
- Empirical Formula: C14H13NO4S
- Molecular Weight: 291.32
- MDL number: MFCD13194810
- EINECS: 692-179-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-01 17:24:31
What is Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate?
Description
Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate is a pharmaceutical intermediate used in the preparation of the xanthine oxidase inhibitor febuxostat, which is used in the treatment of hyperuricaemia and gout. It is also used in the synthesis of novel thiazolyl α-aminophosphonates.
Chemical properties
Yellow or yellow powder
The Uses of Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate is a product prepared via reaction 4-Hydroxybenzene-1-benzothiomide with ethyl-2-chloro acetoacetate. An antibacterial agent and antifungal activity against C.albicans.
Properties of Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Melting point: | 116 °C |
Boiling point: | 446.7±55.0 °C(Predicted) |
Density | 1.335 |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | 6.81±0.20(Predicted) |
color | Pale Yellow to Yellow |
CAS DataBase Reference | 161798-01-2(CAS DataBase Reference) |
Safety information for Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Computed Descriptors for Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Abamectin manufacturer
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ethyl 2-(4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
ETHYL 2-(3-FORMYL-4-ISOBUTOXYPHENYL)-4-METHYLTHIAZOLE-5-CARBOXYLATE
4-HYDROXYTHIOBENZAMIDE
Ethyl 2-(3-bromo-4-isobutoxyphenyl)- 4-methyl-5-thiazolecarboxylate
3-Cyano-4-(2-methylpropoxy)benzenecarbothioamide
Ethyl 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate
Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
Febuxostat
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