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HomeProduct name listDoxycycline hydrochloride

Doxycycline hydrochloride

Synonym(s):α-6-Deoxy-5-hydroxytetracycline hydrochloride;Doxylin;Idocyklin;Vibramycin hyclate;Vibramycin hydrochloride

  • CAS NO.:10592-13-9
  • Empirical Formula: C22H25ClN2O8
  • Molecular Weight: 480.9
  • MDL number: MFCD03427564
  • EINECS: 234-198-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 23:02:33
Doxycycline hydrochloride Structural

What is Doxycycline hydrochloride?

Chemical properties

Yellow Crystalline powder

The Uses of Doxycycline hydrochloride

Doxycycline hydrochloride is a salt prepared from doxycycline taking advantage of the basic dimethylamino group which protonates and readily forms a salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, doxycycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis.

The Uses of Doxycycline hydrochloride

antibiotic

The Uses of Doxycycline hydrochloride

Doxycycline hydrochloride, is used to eliminate Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and to eliminate Ixodes scapularis ticks. It is a broad spectrum inhibitor used to inhibit matrix metalloproteinases (MMP), such as type 1 collagenase in studies on wound healing and tissue remodeling.

Definition

ChEBI: The hydrochloride salt of doxycycline.

Properties of Doxycycline hydrochloride

Melting point: 195-201℃
Flash point: 87℃
storage temp.  Inert atmosphere,2-8°C
solubility  H2O: 50 mg/mL, clear, yellow-green
form  powder
color  yellow
Water Solubility  Soluble in water.
CAS DataBase Reference 10592-13-9(CAS DataBase Reference)

Safety information for Doxycycline hydrochloride

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Health Hazard
GHS08
GHS Hazard Statements H302:Acute toxicity,oral
Precautionary Statement Codes P202:Do not handle until all safety precautions have been read and understood.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313:IF exposed or concerned: Get medical advice/attention.

Computed Descriptors for Doxycycline hydrochloride

InChIKey RUYHIJHUVHIMIR-PGTYNCOMNA-N
SMILES O[C@@]12C(C(C(=O)N)=C(O)[C@@H](N(C)C)[C@]1([H])[C@H]([C@]1([H])[C@H](C3C=CC=C(O)C=3C(=O)C1=C2O)C)O)=O.Cl |&1:1,9,13,15,16,18,r|

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