Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listDIMETHYLZINC

DIMETHYLZINC

  • CAS NO.:544-97-8
  • Empirical Formula: C2H6Zn
  • Molecular Weight: 95.46
  • MDL number: MFCD00014854
  • EINECS: 208-884-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-12-15 17:16:12
DIMETHYLZINC Structural

What is DIMETHYLZINC?

Chemical properties

Clear colorless liquid

The Uses of DIMETHYLZINC

Dimethylzinc is pharmaceutical compound comprising Hemiasterlin derivatives and its antibody conjugate for treatment of cancer.

The Uses of DIMETHYLZINC

Activator for radical trifluoromethylation of silyl enol ethers leading to α-trifluoromethyl ketones.1

The Uses of DIMETHYLZINC

Dimethylzinc solution can be used as:

  • A catalyst with nickel for the stereoselective C?2 alkenylation and dialkenylation of pyridine derivatives by alkynes to give monoalkenylation products.
  • A reagent with aldehydes and 2-methoxyaniline for the synthesis of enantioselective alkyl and aralkyl secondary amines via one-pot three-component coupling reaction in the presence of zirconium tetraisopropoxide.
  • A methylating reagent for methylation of fluoroalkylated pyruvates in the presence of copper/chiral diphosphine catalyst.

Definition

ChEBI: Dimethylzinc is a dialkylzinc compound.

General Description

Mobile liquid, with peculiar garlic odor.

Air & Water Reactions

Highly flammable. Ignites in air and burns with a blue flame giving off a peculiar garlicky odor. Explodes in oxygen or ozone. Reacts violently with water to generate methane [Merck, 11th ed., 1989; Brauer(1965)]. Very slow oxidation with traces of air to give methylzinc methylate.

Reactivity Profile

DIMETHYLZINC is very reactive, acts as a strong reducing agent. Combines with acids, with alcohols (methanol, ethanol), and 2-2-dichloropropane as well as with water with explosive violence. When heated to decomposition emits toxic fumes of zinc oxide [Bretherick, 5th ed., 1995, p. 354]. Oxidants may yield peroxide formation, which is explosive.

Health Hazard

Inhalation of mist or vapor causes immediate irritation of upper respiratory tract. Excessive or prolonged inhalation of fumes from ignition or decomposition may cause ``metal fume fever'' (sore throat, headache, fever, chills, nausea, vomiting, muscular aches, perspiration, constricting sensation in lungs, weakness, sometimes prostration). Symptoms usually last 12-24 hrs. Eyes are immediately and severely irritated by liquid, vapor, or dilute solutions. If not removed by thorough flushing with water, chemical may permanently damage cornea. Skin will undergo thermal and acid burns when chemical reacts with moisture in skin. Unless washed quickly, skin may be scarred. Treat dilute solutions with same precautions as concentrated liquid. Ingestion, while unlikely, would cause immediate burns at site of contact. Nausea, vomiting, cramps, and diarrhea may follow. Tissues may ulcerate if not treated.

Properties of DIMETHYLZINC

Melting point: -42°C
Boiling point: 44-46 °C
Density  0.92 g/mL at 20 °C
Flash point: 30 °F
storage temp.  0-6°C
form  liquid
color  colorless
Sensitive  Air & Moisture Sensitive
Merck  14,3263
BRN  3587195
CAS DataBase Reference 544-97-8(CAS DataBase Reference)
EPA Substance Registry System Zinc, dimethyl- (544-97-8)

Safety information for DIMETHYLZINC

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
ghs
Health Hazard
GHS08
ghs
Environment
GHS09
GHS Hazard Statements H225:Flammable liquids
H250:Pyrophoric liquids; Pyrorophoric solids
H252:Self-heating substances and mixtures
H260:Substances And Mixtures Which, In Contact With Water,Emit Flammable Gases
H261:Substances And Mixtures Which, In Contact With Water,Emit Flammable Gases
H304:Aspiration hazard
H314:Skin corrosion/irritation
H318:Serious eye damage/eye irritation
H336:Specific target organ toxicity,single exposure; Narcotic effects
H373:Specific target organ toxicity, repeated exposure
H400:Hazardous to the aquatic environment, acute hazard
H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P222:Do not allow contact with air.
P223:Keep away from any possible contact with water, because of violent reaction and possible flash fire.
P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P273:Avoid release to the environment.
P231+P232:Handle under inert gas. Protect from moisture.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P370+P378:In case of fire: Use … for extinction.
P405:Store locked up.
P422:Store contents under …

Computed Descriptors for DIMETHYLZINC

InChIKey AXAZMDOAUQTMOW-UHFFFAOYSA-N

Related products of tetrahydrofuran

You may like

  • Di Methyl Zinc 1.5M in Toleuene 544-97-8 99%
    Di Methyl Zinc 1.5M in Toleuene 544-97-8 99%
    544-97-8
    View Details
  • 544-97-8 Dimethylzinc solution, 1.5M in Toluene 99%
    544-97-8 Dimethylzinc solution, 1.5M in Toluene 99%
    544-97-8
    View Details
  • Dimethylzinc solution CAS 544-97-8
    Dimethylzinc solution CAS 544-97-8
    544-97-8
    View Details
  • Dimethylzinc solution CAS 544-97-8
    Dimethylzinc solution CAS 544-97-8
    544-97-8
    View Details
  • Dimethyl Zinc (2.0M in Toluene)
    Dimethyl Zinc (2.0M in Toluene)
    544-97-8
    View Details
  • 544-97-8 DI-METHYL ZINC (1.0 M IN TOLUENE)
    544-97-8 DI-METHYL ZINC (1.0 M IN TOLUENE)
    544-97-8
    View Details
  • Dimethyl Zinc 1.0 M in Hexane CAS 544-97-8
    Dimethyl Zinc 1.0 M in Hexane CAS 544-97-8
    544-97-8
    View Details
  • Dimethyl Zinc  1.0 M in Heptane CAS 544-97-8
    Dimethyl Zinc 1.0 M in Heptane CAS 544-97-8
    544-97-8
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.