Dimethyl chloromalonate

CAS NO.：28868-76-0
Empirical Formula: C5H7ClO4
Molecular Weight: 166.56
MDL number: MFCD00042837
EINECS: 249-275-0
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 17:06:38

What is Dimethyl chloromalonate?

The Uses of Dimethyl chloromalonate

Dimethyl chloromalonate is suitable for use in the synthesis of 4,5,6-trichloropyrimidine. It may be used in the stereoselective synthesis of highly functionalized nitrocyclopropanes. It may be used in one-pot synthesis of tetra-alkoxycarbonylallylidenetriphenylphosphoranes.

General Description

Dimethyl chloromalonate (dimethyl 2-chloromalonate) is a dialkyl 2-substituted malonate. Carbanions of dimethyl chloromalonate are reported to react with naphthoquinone derivatives, via vicarious nucleophilic substitution or oxidative nucleophilic substitution of hydrogen processes. Dimethyl chloromalonate is reported to react with hydroquinone and monosubstituted hydroquinones to afford 2-oxido-benzo[b]furan derivatives. Synthesis of dimethyl 2-chloromalonate, via chlorination of dimethyl malonate has been reported.

Properties of Dimethyl chloromalonate

Boiling point:	105-106 °C/19 mmHg (lit.)
Density	1.305 g/mL at 25 °C (lit.)
refractive index	n20/D 1.437(lit.)
Flash point:	224 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	clear liquid
pka	9.02±0.46(Predicted)
color	Colorless to Light yellow
BRN	1768415
CAS DataBase Reference	28868-76-0(CAS DataBase Reference)

Safety information for Dimethyl chloromalonate

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.