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HomeProduct name listDehydroepiandrosterone acetate

Dehydroepiandrosterone acetate

Synonym(s):3-β-Acetoxy-5-androsten-17-one;Prasterone acetate

  • CAS NO.:853-23-6
  • Empirical Formula: C21H30O3
  • Molecular Weight: 330.47
  • MDL number: MFCD00021119
  • EINECS: 212-714-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-03-22 17:12:53
Dehydroepiandrosterone acetate Structural

What is Dehydroepiandrosterone acetate?

Chemical properties

Off-White Solid

The Uses of Dehydroepiandrosterone acetate

A metabolite of Dehydroepiandrosterone. This mammalian pro-hormone promotes brain and immune function

The Uses of Dehydroepiandrosterone acetate

Menopausal syndrome

Definition

ChEBI: Prasterone acetate is a steroid ester.

Flammability and Explosibility

Not classified

Biological Activity

Dehydroepiandrosterone acetate (DHEA, Androstenolone) is a kind of dehydroepiandrosterone derivatives. DHEA is an endogenous steroid hormone, which is considered to be a natural product/dietary supplement with many proposed benefits to humans.

in vivo

Dehydroisoandrosterone implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of Dehydroisoandrosterone-implanted birds show higher aromatase mRNA expression in the preoptic area (POA) and higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone-induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone levels. Dehydroisoandrosterone supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group.

Properties of Dehydroepiandrosterone acetate

Melting point: 168-170 °C(lit.)
Boiling point: 407.89°C (rough estimate)
Density  1.0998 (rough estimate)
vapor pressure  0Pa at 20℃
refractive index  1.5192 (estimate)
storage temp.  Refrigerator
solubility  Chloroform, DMSO (Slightly), Methanol (Slightly)
form  Solid
color  White to Off-White
optical activity [α]20/D +2.4°, c = 2 in ethanol
Water Solubility  11.5mg/L(temperature not stated)
InChI InChI=1/C21H30O3/c1-13(22)24-15-8-10-20(2)14(12-15)4-5-16-17-6-7-19(23)21(17,3)11-9-18(16)20/h4,15-18H,5-12H2,1-3H3/t15-,16-,17-,18-,20-,21-/s3
CAS DataBase Reference 853-23-6

Safety information for Dehydroepiandrosterone acetate

Computed Descriptors for Dehydroepiandrosterone acetate

InChIKey NCMZQTLCXHGLOK-KJBVPOJVSA-N
SMILES C[C@]12CC[C@H](OC(=O)C)CC1=CC[C@@]1([H])[C@]3([H])CCC(=O)[C@@]3(C)CC[C@]21[H] |&1:1,4,13,15,21,25,r|

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