Dehydroepiandrosterone acetate
Synonym(s):3-β-Acetoxy-5-androsten-17-one;Prasterone acetate
- CAS NO.:853-23-6
- Empirical Formula: C21H30O3
- Molecular Weight: 330.47
- MDL number: MFCD00021119
- EINECS: 212-714-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-03-22 17:12:53
What is Dehydroepiandrosterone acetate?
Chemical properties
Off-White Solid
The Uses of Dehydroepiandrosterone acetate
A metabolite of Dehydroepiandrosterone. This mammalian pro-hormone promotes brain and immune function
The Uses of Dehydroepiandrosterone acetate
Menopausal syndrome
Definition
ChEBI: Prasterone acetate is a steroid ester.
Flammability and Explosibility
Not classified
Biological Activity
Dehydroepiandrosterone acetate (DHEA, Androstenolone) is a kind of dehydroepiandrosterone derivatives. DHEA is an endogenous steroid hormone, which is considered to be a natural product/dietary supplement with many proposed benefits to humans.
in vivo
Dehydroisoandrosterone implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of Dehydroisoandrosterone-implanted birds show higher aromatase mRNA expression in the preoptic area (POA) and higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone-induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone levels. Dehydroisoandrosterone supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group.
Properties of Dehydroepiandrosterone acetate
Melting point: | 168-170 °C(lit.) |
Boiling point: | 407.89°C (rough estimate) |
Density | 1.0998 (rough estimate) |
vapor pressure | 0Pa at 20℃ |
refractive index | 1.5192 (estimate) |
storage temp. | Refrigerator |
solubility | Chloroform, DMSO (Slightly), Methanol (Slightly) |
form | Solid |
color | White to Off-White |
optical activity | [α]20/D +2.4°, c = 2 in ethanol |
Water Solubility | 11.5mg/L(temperature not stated) |
InChI | InChI=1/C21H30O3/c1-13(22)24-15-8-10-20(2)14(12-15)4-5-16-17-6-7-19(23)21(17,3)11-9-18(16)20/h4,15-18H,5-12H2,1-3H3/t15-,16-,17-,18-,20-,21-/s3 |
CAS DataBase Reference | 853-23-6 |
Safety information for Dehydroepiandrosterone acetate
Computed Descriptors for Dehydroepiandrosterone acetate
InChIKey | NCMZQTLCXHGLOK-KJBVPOJVSA-N |
SMILES | C[C@]12CC[C@H](OC(=O)C)CC1=CC[C@@]1([H])[C@]3([H])CCC(=O)[C@@]3(C)CC[C@]21[H] |&1:1,4,13,15,21,25,r| |
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