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HomeProduct name listD-Ephedrine hydrochloride

D-Ephedrine hydrochloride

Synonym(s):(1S,2R)-(+)-α-(1-Methylaminoethyl)benzyl alcohol hydrochloride;(1S,2R)-(+)-2-Methylamino-1-phenyl-1-propanol hydrochloride;D-α-(1-Methylaminoethyl)benzyl alcohol hydrochloride

  • CAS NO.:24221-86-1
  • Empirical Formula: C10H16ClNO
  • Molecular Weight: 201.69
  • MDL number: MFCD00064551
  • EINECS: 246-090-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:08:52
D-Ephedrine hydrochloride Structural

What is D-Ephedrine hydrochloride?

Chemical properties

white crystalline powder

The Uses of D-Ephedrine hydrochloride

α- and β-Adrenergic agonist. Bronchodilator.

Safety Profile

A poison by intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also EPHEDRINE

Purification Methods

Recrystallise the hydrochloride from EtOH/Et2O. The free base crystallises from *C6H6 with m 40-41o (Skita et al. Chem Ber 66 974 1933]. [Beilstein 13 H 254, 13 II 375, 13 III 1721, 13 IV 1879.]

Properties of D-Ephedrine hydrochloride

Melting point: 218-220 °C(lit.)
alpha  34.3 º (c=5, H2O)
Flash point: 9℃
storage temp.  Refrigerator
solubility  DMF: 10 mg/ml; DMSO: 3 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 5 mg/ml
form  A crystalline solid
optical activity [α]23/D +34.3°, c = 5 in H2O
BRN  6118541
CAS DataBase Reference 24221-86-1(CAS DataBase Reference)
EPA Substance Registry System Benzenemethanol, .alpha.-[(1R)-1-(methylamino)ethyl]-, hydrochloride, (.alpha.S)- (24221-86-1)

Safety information for D-Ephedrine hydrochloride

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Health Hazard
GHS08
GHS Hazard Statements H225:Flammable liquids
H370:Specific target organ toxicity, single exposure
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for D-Ephedrine hydrochloride

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