CLOTHIAPINE
- CAS NO.：2058-52-8
- Empirical Formula: C18H18ClN3S
- Molecular Weight: 343.87
- MDL number: MFCD00866705
- EINECS: 218-162-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is CLOTHIAPINE?
The Uses of CLOTHIAPINE
Antipsychotic.
Background
Clothiapine has been approved in European countries and is an atypical antipsychotic, shown to be useful in some treatment-resistant patients.
What are the applications of Application
Clothiapine is a dibenzothiazepine analog of quetiapine
Definition
ChEBI: Clotiapine is a dibenzothiazepine.
Safety Profile
Poison by ingestion. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl-, NOx, and SOx.
Metabolism
Not Available
Properties of CLOTHIAPINE
| Melting point: | 121-123℃ |
| Boiling point: | 163.4°C (rough estimate) |
| Density | 1.2405 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| pka | 7.22±0.42(Predicted) |
| form | Off-white solid (m.p. 118-120°C). |
| color | White to light yellow |
| Stability: | Hygroscopic |
Safety information for CLOTHIAPINE
Computed Descriptors for CLOTHIAPINE
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ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
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