Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listFluphenazine decanoate

Fluphenazine decanoate

  • CAS NO.:5002-47-1
  • Empirical Formula: C32H44F3N3O2S
  • Molecular Weight: 591.77
  • MDL number: MFCD00798504
  • EINECS: 225-672-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-07-02 08:54:57
Fluphenazine decanoate  Structural

What is Fluphenazine decanoate ?

Chemical properties

Yellow Oil

The Uses of Fluphenazine decanoate

Fluphenazine Decanoate is used in psychotropic drug treatments like those relating to schizophrenia. Antipsychotic.

Definition

ChEBI: Fluphenazine decanoate is the prodrug of fluphenazine, an antipsychotic drug used for the symptomatic management of psychosis in patients with schizophrenia. It has a role as a phenothiazine antipsychotic drug, a prodrug and a dopaminergic antagonist. It is a member of phenothiazines, a decanoate ester, an organofluorine compound and a N-alkylpiperazine. It is functionally related to a fluphenazine.

Clinical Use

Antipsychotic
Schizophrenia and other psychoses

Drug interactions

Potentially hazardous interactions with other drugs
Anaesthetics: enhanced hypotensive effect.
Analgesics: increased risk of convulsions with tramadol; enhanced hypotensive and sedative effects with opioids.
Anti-arrhythmics: increased risk of ventricular arrhythmias with anti-arrhythmics that prolong the QT interval; increased risk of ventricular arrhythmias with amiodarone and dronedarone - avoid; increased risk of ventricular arrhythmias with disopyramide.
Antibacterials: increased risk of ventricular arrhythmias with delamanid and moxifloxacin - avoid
Antidepressants: increased risk of ventricular arrhythmias with tricyclics, citalopram, escitalopram; possible increased risk of convulsions with vortioxetine
Antiepileptics: antagonises anticonvulsant effect.
Antimalarials: increased risk of ventricular arrhythmias with artenimol with piperaquine and artemether/lumefantrine - avoid.
Antipsychotics: increased risk of ventricular arrhythmias with droperidol, pimozide and risperidone - avoid; avoid use of depot formulations with clozapine (cannot be withdrawn quickly if neutropenia occurs).
Antivirals: increased risk of ventricular arrhythmias with saquinavir - avoid; concentration possibly increased with ritonavir.
Anxiolytics and hypnotics: increased sedative effects
Atomoxetine: increased risk of ventricular arrhythmias.
Beta-blockers: enhanced hypotensive effect; increased risk of ventricular arrhythmias with sotalol
Cytotoxics: increased risk of ventricular arrhythmias with arsenic trioxide
Diuretics: enhanced hypotensive effect.
Lithium: increased risk of extrapyramidal side effects and possibly neurotoxicity.
Pentamidine: increased risk of ventricular arrhythmias - avoid.
Avoid with drugs that prolong the QT interval.

Metabolism

The cytochrome P450 isoenzyme CYP2D6 is involved in fluphenazine metabolism.

Properties of Fluphenazine decanoate

Melting point: 30-32°
Boiling point: 658.1±55.0 °C(Predicted)
Density  1.149±0.06 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  Practically insoluble in water, very soluble in ethanol and in methylene chloride, freely soluble in methanol.
form  neat
pka 7.32±0.10(Predicted)
form  Oil
color  Light yellow to yellow
CAS DataBase Reference 5002-47-1

Safety information for Fluphenazine decanoate

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Health Hazard
GHS08
GHS Hazard Statements H300:Acute toxicity,oral
H361:Reproductive toxicity
Precautionary Statement Codes P201:Obtain special instructions before use.
P202:Do not handle until all safety precautions have been read and understood.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Computed Descriptors for Fluphenazine decanoate

Abamectin manufacturer

R L Fine Chem Pvt. Ltd

1Y
Phone:+91-8042488999
product: 5002-47-1 Fluphenazine decanoate 98%
Inquiry

Global Calcium Pvt Ltd

1Y
Phone:+91-8040554500
Whatsapp: +91 8040554500
product: 5002-47-1 99%
Inquiry

Ralington Pharma

1Y
Phone:+91-9687771722
Whatsapp: +91- 9687771722
product: Fluphenazine decanoate 98%
Inquiry

Gland Pharma Ltd

1Y
Phone:+91-9700602423
Whatsapp: +91-9700602423
product: Fluphenazine decanoate 5002-47-1 98%
Inquiry

Century Pharmaceuticals Ltd

1Y
Phone:+91-2652361581
product: 5002-47-1 Fluphenazine decanoate 99%
Inquiry

Asence Pharma Pvt Ltd

1Y
Phone:+91-265228317
product: 5002-47-1 Fluphenazine decanoate 99%
Inquiry

Flowchem Pharma Pvt Ltd

1Y
Phone:+91-9845055636
Whatsapp: +91- 9845055636
product: Fluphenazine decanoate 98%
Inquiry

Samchem India

Delhi
Phone:91-8470038886
Whatsapp: 91-8470038886
product: Fluphenazine decanoate
Inquiry

Gia Pharma

Vadodara
Phone:91-7490864011
Whatsapp: 91-7490864011
product: Fluphenazine decanoate
Inquiry

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.