cloprednol
- CAS NO.：5251-34-3
- Empirical Formula: C21H25ClO5
- Molecular Weight: 392.876
- MDL number: MFCD00200364
- EINECS: 2260526
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-10-28 16:00:23
What is cloprednol?
Originator
Syntestan,Syntex,W. Germany,1980
The Uses of cloprednol
A systematic corticosteroid. Anti-inflammatory.
Definition
ChEBI: Cloprednol is a 21-hydroxy steroid.
Manufacturing Process
A mixture of 5 g of the 21-acetate of 6α-chlorohydrocortisone, 7 g of chloranil and 100 cc of n-amyl alcohol was refluxed for 16 hours, cooled and diluted with ether. The solution was successively washed with water, 5% sodium carbonate solution and water, dried over anhydrous sodium sulfate, filtered and evaporated to dryness under reduced pressure. Chromatographic purification of the residue yielded the 21-acetate of 6-chloro-δ1,4,6- pregnatriene-11β,17α,21-triol-3,20-dione.
Therapeutic Function
Glucocorticoid
Properties of cloprednol
| Melting point: | >125°C (dec.) |
| Boiling point: | 600.3±55.0 °C(Predicted) |
| Density | 1.40±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 12.30±0.70(Predicted) |
| color | White to Off-White |
Safety information for cloprednol
Computed Descriptors for cloprednol
cloprednol manufacturer
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