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HomeProduct name listChlorohydroquinone

Chlorohydroquinone

Synonym(s):2-Chloro-1,4-dihydroxybenzene

  • CAS NO.:615-67-8
  • Empirical Formula: C6H5ClO2
  • Molecular Weight: 144.56
  • MDL number: MFCD00002341
  • EINECS: 210-442-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-15 19:19:13
Chlorohydroquinone Structural

What is Chlorohydroquinone?

Chemical properties

light brown to grey fine crystalline powder. It precipitates leafy crystals from chloroform and needle-like crystals from toluene. Freely soluble in water and alcohol, slightly soluble in ether and hot chloroform.

The Uses of Chlorohydroquinone

Chlorohydroquinone is a component of polyethers based on organotin with potential application to breast cancer treatment via growth inhibition. Also a component in the synthesis of contraceptive agents in pharmaceutical compounds. It is also used within hydroxylation and catalysis organic reactions in the synthesis of pharmacologically active phenolic compounds.

What are the applications of Application

Chlorohydroquinone is a chlorinated hydroxyphenol

Definition

ChEBI: Chlorohydroquinone is a benzenediol that consists of hydroquinone bearing a single chloro substituent. It has a role as a metabolite. It is a member of monochlorobenzenes and a member of chlorohydroquinones.

Preparation

Chlorohydroquinone is obtained by reacting p-benzoquinone with hydrochloric acid. First dissolve p-benzoquinone with chloroform and pass dry hydrogen chloride gas under cooling to obtain.

What are the applications of Application

Chlorohydroquinone is a benzenediol that consists of hydroquinone bearing a single chloro substituent. It has a role as a metabolite. It is a member of monochlorobenzenes and a member of chlorohydroquinones. Chlorohydroquinone is used in photographic developing solutions. It is also a bactericide.

Safety Profile

Poison by ingestion and intraperitoneal routes. Moderately toxic by skin contact. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl-. See also CHLORIDES.

Purification Methods

Crystallise the hydroquinone from CHCl3 or toluene. [Beilstein 6 IV 5767.]

Properties of Chlorohydroquinone

Melting point: 100-104 °C (lit.)
Boiling point: 263 °C (lit.)
Density  1.2558 (rough estimate)
refractive index  1.4620 (estimate)
Flash point: 263°C
storage temp.  Inert atmosphere,Room Temperature
solubility  DMSO (Slightly), Methanol (Slightly)
form  Fine Crystalline Powder
pka 9.21±0.18(Predicted)
color  Light brown to gray
Water Solubility  soluble
BRN  636835
CAS DataBase Reference 615-67-8(CAS DataBase Reference)
NIST Chemistry Reference 1,4-Benzenediol, 2-chloro-(615-67-8)
EPA Substance Registry System Chlorohydroquinone (615-67-8)

Safety information for Chlorohydroquinone

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H317:Sensitisation, Skin
H318:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for Chlorohydroquinone

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