Chlorogenic acid

Description

Chlorogenic acid is an ester formed from caffeic acid and?L-quinic acid. Despite its name, it contains no chlorine atoms; scientists created the name after they observed that the acid turns the green color of chlorine gas when oxidized. An important factor in plant metabolism, it was first isolated from coffee beans in 1920 by K. Freudenberg. Chlorogenic acid and its isomers also occur in the fruit, leaves, and other tissues of dicotyledenous plants.



The chlorogenic acids in coffee beans are destroyed when the beans are roasted. But J. A. Vinson and colleagues at the University of Scranton (PA) recently found that consuming the chlorogenic acid–rich extracts of green coffee beans promotes weight loss and improves glucose tolerance in humans.



[Even though the use of chlorogenic acids for weight loss appears to be in the developmental phase, DietWorks (Caldwell, NJ) is marketing a green coffee bean extract dietary supplement that it calls “a clinically tested weight management formula”.—Ed.]

The Uses of Chlorogenic acid

A major component of green coffee the extracts of which promote weight loss in overweight and obese people. Chlorogenic Acid is an important intermediate in lignin biosynthesis. Chlorogenic Acid is an antioxidant and an inhibitor of the tumor promoting activity of phorbol ester. It has protective effect against streptozotocin-nicotinamide generated oxidative stress induced diabetes and may also pr otect against cardiovascular disease.

What are the applications of Application

Chlorogenic Acid is a Bcr-Abl inhibitor