Cartap

CAS NO.：15263-53-3
Empirical Formula: C7H15N3O2S2
Molecular Weight: 237.34
MDL number: MFCD00143932
EINECS: 620-418-2
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-04 17:34:34

What is Cartap?

Chemical properties

solid

The Uses of Cartap

Cartap is obtained by hydrolyzing 1,1-dithiocyanato- 2-dimethylaminopropane with hydrochloric acid. Cartap is the pro-insecticide of the natural toxin nereistoxin. It is used for the control of chewing and sucking insects, at almost all stages of development, on many crops. Its structure is based on that of the naturally occurring neurotoxin, nereistoxin.

Definition

ChEBI: Cartap is a nereistoxin analogue insecticide.

Metabolism

Cartap is hydrolyzed in base to the dihydronereistoxin, which is oxidized to the insecticide, nereistoxin (32). The conversion occurs within plants, and the monoxide (33)was identified as aminor metabolite. In rats, cartap was rapidly excreted in urine. It was hydrolyzed, converted to the sulfoxide, and N-demethylated (9).

Toxicity evaluation

Nereistoxin does not inhibit cholinesterase. Instead, it acts as an antagonist at the nicotinic acetylcholine receptor and blocks neural transmission (10).

Properties of Cartap

Melting point:	130.5-131° (dec)
Boiling point:	407.2±55.0 °C(Predicted)
Density	1.309±0.06 g/cm3(Predicted)
Water Solubility	3 mg l^-1 (20 °C, pH 5)
pka	7.61 (base)
Stability:	Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	15263-53-3(CAS DataBase Reference)
EPA Substance Registry System	Carbamothioic acid, S,S'-[2-(dimethylamino)-1,3-propanediyl] ester (15263-53-3)