C6-NBD-CERAMIDE
- CAS NO.:94885-02-6
- Empirical Formula: C30H49N5O6
- Molecular Weight: 575.74
- MDL number: MFCD00467024
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is C6-NBD-CERAMIDE?
Description
C6 NBD ceramide is a biologically active fluorescent analog of short chain, membrane-
Chemical properties
Rust or Dark Yellow Solid
The Uses of C6-NBD-CERAMIDE
A vital fluoresent stain for the Golgi apparatus.
Definition
ChEBI: N-{6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoyl}sphingosine is an N-acylsphingosine that is sphingosine with the amino nitrogen converted into a 6-{[N-(7-nitrobenzo-2,1,3-oxadiazol-4-yl)amino]}hexananamido group. It has a role as a fluorescent probe.
References
Chazotte (2012),?Labeling Golgi with Fluorescent Ceramides;?Cold Spring Harb. Protoc. (8):pdb.prot070599 van Meer et al. (1987),?Sorting of sphingolipids in epithelial (Madin-Darby canine kidney) cells; J. Cell Biol.?105 1623 Don and Rosen (2008),?A fluorescent plate reader assay for ceramide kinase; Anal. Biochem.?375 265 Nikolova-Karakashian (2021),?Methods to Characterize Synthesis and Degradation of Sphingomyelin at the Plasma Membrane and Its Impact on Lipid Raft Dynamics; Methods Mol. Biol.?2187 113
Properties of C6-NBD-CERAMIDE
Melting point: | 85-88 °C |
Density | 1.153±0.06 g/cm3(Predicted) |
storage temp. | −20°C |
solubility | Soluble in DMSO (35 mg/mL) |
form | solid |
pka | 13.54±0.20(Predicted) |
color | Orange |
Stability: | Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. |
Safety information for C6-NBD-CERAMIDE
Computed Descriptors for C6-NBD-CERAMIDE
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