butetamate
- CAS NO.:14007-64-8
- Empirical Formula: C16H25NO2
- Molecular Weight: 263.38
- EINECS: 237-817-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:33
What is butetamate ?
Originator
Butetamat-dihydrogencitrat,Chemische Werke Hommel GmbH and Co.KG
Definition
ChEBI: Butetamate is an alkylbenzene.
Manufacturing Process
16.4 parts of alpha-phenylbutiric acid, 17.5 parts of beta-diethylaminoethylchloride hydrochloride and 35 parts of dry potassium
carbonate in 60 parts diisopropyl ether was stirred for 18 hours under reflux.
To the reaction mixture at 40°C was added 120 parts of the water. Organic
layer was washed with the water. The solvent was removed and the 2-
(diethylamino)ethyl-2-phenylbutyrate was distilled at 167-168°C/10 mm;
melting point of hydrochloride 167-169°C.
In practice it is usually used as citrate.
Therapeutic Function
Anticholinergic, Spasmolytic, Antitussive
Properties of butetamate
Boiling point: | bp11 167-169° |
Density | 0.9903 (rough estimate) |
refractive index | nD20 1.4909 |
pka | 9.22±0.25(Predicted) |
Safety information for butetamate
Computed Descriptors for butetamate
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2-DIETHYLAMINOETHYL 1-(4-NITROPHENYL)CYCLOPENTANECARBOXYLATE HYDROCHLORIDE
butetamate
PRE-084
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REVATROPATE
DROFENINE HYDROCHLORIDE
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PROADIFEN HYDROCHLORIDE
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