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HomeProduct name listBromoacetyl bromide

Bromoacetyl bromide

  • CAS NO.:598-21-0
  • Empirical Formula: C2H2Br2O
  • Molecular Weight: 201.84
  • MDL number: MFCD00000115
  • EINECS: 209-923-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-07 13:31:19
Bromoacetyl bromide Structural

What is Bromoacetyl bromide?

Chemical properties

dark brown-yellow liquid

The Uses of Bromoacetyl bromide

Bromoacetyl bromide is widely used in the synthesis of fine chemicals, agrochemicals, dyes and pharmaceuticals. As an acylating agent, it reacts with 10H-phenothiazine to give 10-bromoacetyl-10H-phenothiazine. Similarly, it is also involved in the preparation of bromoactylated starch which is a biodegradable thermoplastic copolymer.

General Description

A water-white liquid with a pungent odor. Denser than water. Irritates skin, eyes and mucous membranes. May be toxic by ingestion, inhalation and skin absorption. Used to make other chemicals.

Air & Water Reactions

Fumes in air. Reacts violently with water to form hydrobromic acid (HBr) (USCG 1991).

Reactivity Profile

Bromoacetyl bromide is incompatible with water, with bases (including amines), with strong oxidizing agents, with alcohols. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291]. Decomposes when heated with evolution of highly toxic and irritating hydrogen bromide and bromophosgene vapors.

Health Hazard

Inhalation causes severe irritation of upper respiratory system. External contact causes severe irritation of eyes and skin. Ingestion causes severe irritation of mouth and stomach.

Properties of Bromoacetyl bromide

Melting point: 148.5°C (estimate)
Boiling point: 147-150 °C(lit.)
Density  2.324 g/mL at 20 °C
vapor pressure  3.8 mm Hg ( 25 °C)
refractive index  n20/D 1.547(lit.)
Flash point: >105°C
storage temp.  Refrigerator (+4°C)
solubility  soluble in Chloroform
form  Powder
color  White
Water Solubility  REACTS
Sensitive  Moisture Sensitive
BRN  605440
Dielectric constant 12.6(20℃)
Stability: Stable, but reacts violently with water. Incompatible with water, moisture, alcohols, strong bases, strong oxidizing agents.
CAS DataBase Reference 598-21-0(CAS DataBase Reference)
NIST Chemistry Reference Bromoacetyl bromide(598-21-0)
EPA Substance Registry System Acetyl bromide, 2-bromo- (598-21-0)

Safety information for Bromoacetyl bromide

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H314:Skin corrosion/irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P363:Wash contaminated clothing before reuse.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for Bromoacetyl bromide

InChIKey LSTRKXWIZZZYAS-UHFFFAOYSA-N

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