Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listBromo-tris-pyrrolidino-phosphonium hexafluorophosphate

Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate

Synonym(s):Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate;PyBroP

  • CAS NO.:132705-51-2
  • Empirical Formula: C12H24BrF6N3P2
  • Molecular Weight: 466.19
  • MDL number: MFCD00077412
  • EINECS: 620-834-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate Structural

What is Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate?

Chemical properties

white to off-white powder

The Uses of Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate

A stable reagent for the coupling of N-Methylamino acids in peptide synthesis.

The Uses of Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate

It can be used as a coupling reagent:

  • For Suzuki–Miyaura cross-coupling of phenols and arylboronic acids to synthesize biaryls and heterobiaryls.
  • To functionalize pyrimidines (synthesized from 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) via the Kappe dehydrogenation) by using various nucleophiles.
  • To synthesize formamidines by coupling with various primary amines and N,N-diisopropylethylamine.

It can also be used as an activating reagent:
  • For the activation of C-OH bond in tautomerizable heterocycles to form the phosphonium salt which aids the Sonogashira coupling of heterocycles with various alkynes.
  • For the one–pot activation of C-O bond in phenols and further coupling reaction with phosphine oxide or phosphite to form C-P bonds.

Properties of Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate

Melting point: 100 °C
storage temp.  -20°C
solubility  DMF: 0.4 g/mL, clear
form  Powder
color  White to off-white
Water Solubility  moderately soluble
Sensitive  Moisture Sensitive
BRN  7845702
Stability: Moisture Sensitive
CAS DataBase Reference 132705-51-2(CAS DataBase Reference)

Safety information for Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H314:Skin corrosion/irritation
Precautionary Statement Codes P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P363:Wash contaminated clothing before reuse.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate

InChIKey CYKRMWNZYOIJCH-UHFFFAOYSA-N

Related products of tetrahydrofuran

You may like

  • Bromotripyrrolidinophosphonium Hexafluorophosphate CAS 132705-51-2
    Bromotripyrrolidinophosphonium Hexafluorophosphate CAS 132705-51-2
    132705-51-2
    View Details
  • Pybrop 97% CAS 132705-51-2
    Pybrop 97% CAS 132705-51-2
    132705-51-2
    View Details
  • PyBroP CAS 132705-51-2
    PyBroP CAS 132705-51-2
    132705-51-2
    View Details
  • Bromotripyrrolidinophosphonium hexafluorophosphate CAS 132705-51-2
    Bromotripyrrolidinophosphonium hexafluorophosphate CAS 132705-51-2
    132705-51-2
    View Details
  • 177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane 98+
    177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane 98+
    177-11-7
    View Details
  • 217299-03-1 98+
    217299-03-1 98+
    217299-03-1
    View Details
  • 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 39124-20-4 98+
    4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 39124-20-4 98+
    39124-20-4
    View Details
  • 39856-50-3 98+
    39856-50-3 98+
    39856-50-3
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.