Boc-Thr(Bzl)-OH

Synonym(s):N-(tert-Butoxycarbonyl)-O-benzyl-L-threonine;Boc-O-benzyl-L-threonine;Boc-Thr(Bzl)-OH;N-α-t.-Boc-O-benzyl-L-threonine

CAS NO.：15260-10-3
Empirical Formula: C16H23NO5
Molecular Weight: 309.36
MDL number: MFCD00066062
EINECS: 239-304-5
SAFETY DATA SHEET (SDS)
Update Date: 2023-09-27 22:32:06

What is Boc-Thr(Bzl)-OH?

Chemical properties

White crystalline

The Uses of Boc-Thr(Bzl)-OH

Boc-O-benzyl-L-threonine, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.

What are the applications of Application

Boc-Thr(Bzl)-OH is a standard building block for introduction of threonine amino-acid residues by Boc SPPS.

Properties of Boc-Thr(Bzl)-OH

Melting point:	80-82 °C(lit.)
Boiling point:	461.5±45.0 °C(Predicted)
alpha	22 º (c=2 in 95% ethanol)
Density	1.152±0.06 g/cm3(Predicted)
refractive index	16.5 ° (C=1, MeOH)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	powder to crystal
pka	3.50±0.10(Predicted)
color	White to Almost white
optical activity	[α]20/D +16.5±1°, c = 1% in methanol
BRN	3065591
InChI	InChI=1S/C16H23NO5/c1-11(21-10-12-8-6-5-7-9-12)13(14(18)19)17-15(20)22-16(2,3)4/h5-9,11,13H,10H2,1-4H3,(H,17,20)(H,18,19)/t11-,13+/m1/s1
CAS DataBase Reference	15260-10-3(CAS DataBase Reference)
EPA Substance Registry System	L-Threonine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)- (15260-10-3)

Safety information for Boc-Thr(Bzl)-OH

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.