BKM-120
- CAS NO.:1202777-78-3
- Empirical Formula: C18H21F3N6O2
- Molecular Weight: 410.3935496
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-09 09:30:19
What is BKM-120?
The Uses of BKM-120
A selective Class I PI3K inhibitor of p110α, p110β, p110δ and p110γ with IC50s of 50-300 nM.
Definition
ChEBI: An aminopyridine that is 4-(trifluoromethyl)pyridin-2-amine substituted at position 5 by a 2,6-di(morpholin-4-yl)pyrimidin-4-y group. A selective PI3K inhibitor with anti-tumour properties.
Properties of BKM-120
CAS DataBase Reference | 1202777-78-3 |
Safety information for BKM-120
Computed Descriptors for BKM-120
New Products
(R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate Tubulysin I Tubulysin E Tubulysin H 2,2-diethoxyethanethioamide 2,2-Difluoropropanol Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate CYCLOBUTYLAMINE HYDROCHLORIDE 4,4-DIFLUOROPIPERIDINE 4-(Benzyloxy)-3-bromophenylacetic Acid 4,4-DIFLUOROCYCLOHEXANAMINE 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Imeglimin Hydrochloride IH Fuel shell 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 1-Aminoindan Hydrochloride 5-(piperazin-1-yl) benzofuran-2- carboxamide Magnesium Trisilicate Latanoprostene Bunod Lubiprostone Flame Retardant Zinc Borate 1H-Imidazole-4-carbonitrileRelated products of tetrahydrofuran
Lorlatinib (PF-06463922)
Crizotinib
AP26113
Cabozantinib Malate
Brigatinib
BKM120 (NVP-BKM120, Buparlisib)
Niraparib
Ceritinib (LDK378)
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