Biphenyl dimethyl dicarboxylate

CAS NO.：792-74-5
Empirical Formula: C16H14O4
Molecular Weight: 270.28
MDL number: MFCD00017201
EINECS: 212-341-4
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 23:02:33

What is Biphenyl dimethyl dicarboxylate?

Chemical properties

White or cream crystalline powder

The Uses of Biphenyl dimethyl dicarboxylate

Dimethyl biphenyl-4,4'-dicarboxylate is used as a hepatoprotectant in the treatment of chronic hepatitis. At 250 μg/ml, it has been shown to stimulate JAK/STAT signaling and to induce the expression of interferon-α stimulated genes in a HepG2 cell line. It has been used to study hepatic fibrosis and chronic hepatocellular damage. It appears to normalize alanine aminotransferase (ALT) in cases where levels of ALT are elevated. It may be employed as starting reagent for the synthesis of dimethyl 2-fluoro-and 2,2?-difluorobiphenyl-4,4?-dicarboxylates.

What are the applications of Application

Dimethyl biphenyl-4,4′-dicarboxylate is used to study chronic hepatocellular damage

Synthesis Reference(s)

Tetrahedron Letters, 18, p. 4089, 1977 DOI: 10.1016/S0040-4039(01)83434-1

General Description

Dimethyl biphenyl-4,4′-dicarboxylate is a planar biphenyldicarboxylic acid ester. Crystal data of dimethyl biphenyl-4, 4′-dicarboxylate has been reported.

Properties of Biphenyl dimethyl dicarboxylate

Melting point:	213-215 °C (lit.)
Boiling point:	373.4°C (rough estimate)
Density	1.2117 (rough estimate)
refractive index	1.5447 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	Benzene (Slightly, Heated, Sonicated), Chloroform (Slightly, Heated, Sonicated)
form	Solid
color	White to Off-White
Water Solubility	Insoluble in water.
BRN	2055852
CAS DataBase Reference	792-74-5(CAS DataBase Reference)
NIST Chemistry Reference	[1,1'-Biphenyl]-4,4'-dicarboxylic acid, dimethyl ester(792-74-5)
EPA Substance Registry System	[1,1'-Biphenyl]-4,4'-dicarboxylic acid, dimethyl ester (792-74-5)

Safety information for Biphenyl dimethyl dicarboxylate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.