Biphenyl-4,4'-dicarboxylic acid

Synonym(s):4,4′-Bibenzoic acid;4,4′-Dicarboxybiphenyl;4,4′-Diphenyldicarboxylic acid

CAS NO.：787-70-2
Empirical Formula: C14H10O4
Molecular Weight: 242.23
MDL number: MFCD00002554
EINECS: 212-328-3
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-28 16:48:29

Biphenyl-4,4'-dicarboxylic acid Structural

What is Biphenyl-4,4'-dicarboxylic acid?

Chemical properties

White to light beige powder

The Uses of Biphenyl-4,4'-dicarboxylic acid

Dendrimer building block.

What are the applications of Application

Biphenyl-4,4′-dicarboxylic acid is a dendrimer building block

Purification Methods

The dicarboxylic acid is a white amorphous or microcrystalline substance which does not melt or sublime. It is best purified by precipitation of an aqueous alkaline solution with mineral acid, washing well with H2O and drying in vacuo at 100o. It is characterized by conversion to diphenyl-4,4’-dicarbonyl chloride (with PCl5 [Work J Chem Soc 1317 1940], or by phase transfer catalysis with SOCl2 + BuEt3N+Cl-in 1,2-dichloroethane [Burdett Synthesis 441 1991]) which crystallises from *C6H6 with m 184o. The di-acid chloride gives the dimethyl ester with MeOH, and has m 215-217o (plates from MeOH, m’s of 214o and 224o were also reported). The diethyl ester is similarly prepared with EtOH and has m 122o (from EtOH). [Beilstein 9 II 665, 9 III 4519, 9 IV 3563.]

Properties of Biphenyl-4,4'-dicarboxylic acid

Melting point:	>300 °C(lit.)
Boiling point:	482.5±38.0 °C(Predicted)
Density	1.347±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
form	Powder
pka	3.77±0.10(Predicted)
color	White to light beige
BRN	523308
CAS DataBase Reference	787-70-2(CAS DataBase Reference)
EPA Substance Registry System	[1,1'-Biphenyl]-4,4'-dicarboxylic acid (787-70-2)

Safety information for Biphenyl-4,4'-dicarboxylic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.