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HomeProduct name listArprinocide

Arprinocide

  • CAS NO.:55779-18-5
  • Empirical Formula: C12H9ClFN5
  • Molecular Weight: 277.68
  • MDL number: MFCD00867210
  • EINECS: 259-817-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-06-08 17:06:38
Arprinocide Structural

What is Arprinocide?

Chemical properties

Pale Yellow Solid

Originator

Arprinocid,NANJING PHARMA

The Uses of Arprinocide

Arprinocide can be used as a Coccidiostat used in veterinary medicine.

What are the applications of Application

Arprinocid is a coccidiostat or antiprotozoal agent

Definition

ChEBI: Arprinocid is a member of 6-aminopurines.

Manufacturing Process

To a solution of potassium t-butoxide in absolute ethanol slowly adding dry adenine. This mixture was stirred for about 2 h, and then 2-chloro-6- fluorobenzyl chloride was added over a period of about 4 h. The resulting mixture was heated to reflux with stirring and allowed to react for about 42 h, after which it was cooled to about 10°C. The crude product thus formed was isolated by filtration and then washed with ice cold ethanol and ice cold water to yield a 6-amino-9-(2-chloro-6-fluorobenzyl)purine.

brand name

Arpocox (Merck).

Therapeutic Function

Coccidiostatic

Synthesis Reference(s)

The Journal of Organic Chemistry, 43, p. 960, 1978 DOI: 10.1021/jo00399a034

Properties of Arprinocide

Melting point: 245-246°
Boiling point: 504.6±60.0 °C(Predicted)
Density  1.568 g/cm3
storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C
solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
pka 3.91±0.10(Predicted)
color  Pale Yellow to Pale Beige
λmax 260nm(NaOH aq.)(lit.)
CAS DataBase Reference 55779-18-5(CAS DataBase Reference)

Safety information for Arprinocide

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Arprinocide

Related products of tetrahydrofuran

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