Amiloride hydrochloride dihydrate

Chemical properties

Pale yellow or greenish-yellow powder.

The Uses of Amiloride hydrochloride dihydrate

Amiloride hydrochloride dihydrate is used as a calcium channel and sodium channel protein inhibitor. It reduces electrical potential across tubular epithelium, inhibits angiogenesis and inhibits capillary morphogenesis completely and reversibly at approximately 130 ?M. Amiloride ? HCl is an inhibitor of Sodium/Potassium-ATPase Protein. Defines the I2A-amiloride sensitive and I2B-amiloride insensitive imidazoline binding Blocks TRPP3, acid sensing- (ASIC) and mechanogated membrane-ion channels, as well as the Na+/H+ exchanger. Also inhibits urokinase-type plasminogen activator (uPA); has no effect on tissue-type plasminogen activator.

The Uses of Amiloride hydrochloride dihydrate

Diuretic;Antialdosteron

The Uses of Amiloride hydrochloride dihydrate

An epithelial sodium channel blocker

What are the applications of Application

Amiloride hydrochloride dihydrate is an epithelial sodium channel blocker

Definition

ChEBI: A hydrate that is the dihydrate of amiloride hydrochloride.

brand name

Midamor (Merck).